ERYTHROPOIESIS Flashcards
Process of RBC formation
Erythropoiesis
Total mass of RBCs circulating in the peripheral blood and the bone marrow RBC precursors
Erythron
Erythrocytes in the circulation
RBC mass
A term that describes the dynamics of RBC crenation and destruction
Erythrokinetics
Production of defective erythroid precursor cells
Ineffective erythropoiesis
Decrease in the number of RBC precursors in the bone marrow resulting in low RBC production
Insufficient erythropoiesis
Immature hematopoietic cell that is committed to a cell line but cannot be identified morphologically
Progenitor cells
Immature hematopoietic cell that is morphologically identifiable as belonging to a given cell line
Precursor cells
Earliest marker of erythroid differentiation; transferrin receptor
CD71
Chief stimulatory cytokine for RBCs, a major hormone that stimulates the production of erythrocytes
EPO
Primary cell source of EPO
Peritubular interstitial cell (kidneys)
primary target cells of the EPO
BFU-E, and CFU-E
Produced by the pituitary gland and stimulates erythropoiesis directly
GH
Produced by the testes abd stimulates erythropoises indirectly
Testosterone
Produced by the pituitar gland and stimulates erythropoiesis directly
Prolactin
