erythrocytes Flashcards

1
Q

what is the function of erythrocytes?

A

to transport oxygen from the lungs to the body (via oxygenated blood)

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2
Q

where are erythrocytes produced?

A

they are produced in the bone marrow and destroyed in the spleen and liver (to recycle haemoglobin and erythrocytes)

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3
Q

what is the composition of erythrocytes in human blood?

A

it constitutes 99% of cells in the blood

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4
Q

what is the lifespan of erythrocytes?

A

they have a lifespan of 120 days, due to the lack of nucleus that prevents repair and division in cells

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5
Q

what happens when carbon monoxide binds is exposed to erythrocytes

A
  1. carbon monoxide which is odourless, binds tightly with haemoglobin to form carboxybaemoglobin, which is inactivated.
    2, less haemoglobin is available to bind with oxygen , resulting in less oxygen transport around the body
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6
Q

what causes sickle cell anaemia?

A

it happens when the gene that codes for haemoglobin mutates and produces a protein that is hydrophobic and polymerises to form a sickle shape, reducing surface area to volume ratio for oxygen to bind to haemoglobin

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7
Q

how does sickle cell anaemia affect the body?

A

it results in reduced oxygen flow around the body, and the sickle cell shape may clog blood vessels, resulting in organ swelling

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