Equine: airway dysfunction & disease Flashcards

1
Q

Signs of URT disease

A
  • unilateral nasal discharge (cranial to nasal septum)
  • dull areas when sinuses are percussed
  • audible respiratory noise localized to the URT
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2
Q

Signs of mid-lower respiratory tract disease

A
  • increased RE and RR at rest
  • ausculable abnormal respiratory sounds localized to thorax
  • bilateral nasal discharge
  • pleurodynia (pleural pain)
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3
Q

Describe Strangles and this endoscopic finding.

A

retropharyngeal lymph node ruptures in medial chamber of guttural pouch; Strep equi ss equi organisms can remain in the pouch long after disease resolves and thus horses can serve as carriers

image: guttural pouch empyema

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4
Q

Describe Guttural Pouch Mycosis and this endoscopic finding.

A

Aspergillus fumigatus grows on top/penetrates internal carotid a. within guttural pouch -> epistaxis (can be severe/horse can bleed out)

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5
Q

Common clinical signs with Left Laryngeal Hemiplagia

A

noise on inspiration, can worsen with exercise

Function problem of the upper airway

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6
Q

What are two common diseases that affect the Mid-lower RT of horses?

A

Infectious: Equine influenza
Non-infectious: Equine asthma

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7
Q

What is the typical breathing pattern of equine asthma when it becomes severe?

A

Abdominal press with nostril flare

nostril flare b/c they are trying to decrease airflow resistance/increase their Vt

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8
Q

What is the indication if you visulaize a lot of tracheal mucus during an endoscopic exam?

A

directly proportional to amt. of inflammation present -> TTW cytology should also show neutrophilia

TTW cytology: left = neut. inflammation, right = Curschmann's spirals = indicate chronic inflammation

Neut. morphology is not suggestive of infection. –> dx = equine asthma
75% neutrophils (normal is < 15%)

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9
Q

Characteristics of equine asthma

A
  • recurrent, seasonal, chronic dz
  • middle-aged to older horses
  • progresses with time if not properly managed; no cure, but remission can occur:
  • mild = occasional cough, moderate = exercise intol. + more frequent cough, severe = respiratory distress @ rest, nostril flare and heave line, wt loss

Heave Line: The abdominal muscles must work hard to assist with exhaling, and overdevelopment of these muscles produces a line along both sides of the abdomen known as a “heave line.” Wheezing may be caused by airflow through narrowed airways, and is most obvious when the horse is exhaling.

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10
Q

Causes of equine asthma

A
  • exposure to environmental debris (mold, fungus)
  • feeding rounde bale hay (when it rains, the center of the hay gets moldy and concentrated with endotoxins, ammonia, etc.)
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11
Q

What is the purpose of treating equine asthma with corticosteroids and bronchodilators?

A

corticosteroids: reduce airway inflammation
bronchodilatiors: relax airways

corticosteroids: inhaled (human meds) vs systemic (dexamethasone and prednisolone) – start with highest doese and slowly reduce to find LED

bronchodilators: albuterol, clenbuterol (beta-2 agonists) vs Ipratropium (M2-agonist)

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12
Q

Young race horse presents for cough and poor performance. Physical exam in unremarkable, but bronchoalveolar fluid sample cytology shows neutrophilia w/out evidence of infection. What is your diagnosis and how would you treat?

A

Inflammatory Airway Disease (IAD)
- tx = short-course corticosteroids
- early form of asthma

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13
Q

What disease do high performance horses often develop? Pathogenesis and tx?

A

Exercise-Induced Pulmonary Hemorrhage
- during times of high exercise, capillary hydrostatic pressure increases over 100mmHg -> blood vessels rupture into alveoli
- with repeated episodes, the amt. of blood that ruputres out escalates
- tx = lasix therapy short-term, rest long-term

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14
Q

What aspects of the history justify an infectious MLRT diagnosis in horses?

A
  • fever (usually suggests viral)
  • recent exposure to other/new horses, who also show signs of disease
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15
Q

What is Horsemen’s rule for equine pneumonia recovery?

A
  1. temp daily until resolution
  2. rest one week for every day horse had fever
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16
Q

DDx for young foals with signs of infectious lower respiratory disease

A
  • Rhodococcus equi pneumonia
  • Streptococcus equi ss equi pneumonia
  • Parascarid infection/migration
  • other bacterial pneumonia, viral pneumonia

not an all-inclusive list

Rhodococcus equi: will see hyperfirbinogenemia (chronic inflammation/infection)

17
Q

Findings on thoracic u/s?

A

circle = abscess -> if multiple abscesses found throughout the lung, strongly indicative of Rhodococcus equi pneumonia

18
Q

First-choice ABX for Rhodoccocus equi infection and an important side effect.

A

Macrolides (erythromycin, azithromycin, clarithromycin)

  • Macrolides cause anhidrosis (inabiltiy to sweat normally) -> monitor horses temperature closely for hyperthermia!! -> keep foal out of direct sun, place fan on foal during heat of the day