Epithelium Flashcards
Aggregated polyhedral cells
epithelial
several types of fixed and wandering cells
connective
elongated contractile cells
muscles
elongated cells with extremely fine processes
nervous
composed of closely aggregated polyhedral cells adhering strongly to one
another and to a thin layer of ECM
epithelial tissue
functions of epithelium
- Covering, lining and protection
- Absorption
- Secretion
- Filtration
a semipermeable filter for substances
reaching epithelial cells from below
basement membrane
2 parts of basement membrane
- Basal lamina
- Reticular Lamina
functions of basement membrane
- Physical support
- Cell attachment
- Filter
- Guides cell migration
separates apical and basolateral membrane domains
tight junctions or zonula occludens
major transmembrane protein of tight junctions or zonula occludens
- Claudin
- Occludin
firmly anchoring a cell to its neighbors
Adherens Junction (Zonula Adherens)
major transmembrane protein of Adherens Junction (Zonula Adherens)
- Cadherin
- Catenin
resembles a single “spot-weld” and does not form a belt around the
cell
Desmosome (Macula Adherens)
provides points of strong intermediate
filament coupling between adjacent cells,
strengthening the tissue
Desmosome (Macula Adherens)
anchors cytoskeleton to the basal lamina
Hemidesmosome
Major transmembrane link proteins of hemidesmosomes
Integrin