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Histology Lecture > Connective > Flashcards

Connective Flashcards

1
Q

Provide a matrix that supports and physically connects other tissues and cells together to form the organs of the body

A

Connective tissue

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2
Q

2 main classes of connective tissue proper

A
  1. Loose connective tissue
  2. Dense connective tissue
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3
Q

3 main classes of cartilage

A

Hyaline cartilage
Fibrocartilage
Elastic cartilage

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4
Q

2 main classes of bone

A

Compact and spongy bone

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5
Q

Key cell of connective tissue

A

Fibroblasts

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6
Q

What are the cells of connective tissue

A

Fibroblasts
Adipocytes
Macrophages and mononuclear phagocyte system
Mast cells
Plasma cells
Leuckocytes

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7
Q

Synthesize and secrete collagen and elastin

A

Fibroblasts

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8
Q

Specialized cells for storage of triglycerides

A

Adipocytes

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9
Q

Used for turnover, phagocytosis of dead cells and debris, and antigen presentation to lymphocytes

A

Macrophages and mononuclear phagocyte system

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10
Q

cells same as macrophages that is located in the liver

A

kupffer cells

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11
Q

same as macrophages that is located in the central nervous system

A

microglial cells

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12
Q

filled with basophilic secretory granules that often obscure the central nucleus

A

mast cells

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13
Q

What are the 6 molecules from secretory granules

A

heparin
histamine
protease
eosinophil and neutrophil
cytokines
phospholipid

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14
Q

lymphocyte-derived, antibody-producing cells

A

plasma cells

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15
Q

function in connective tissue only for a few hours or days and then undergo apoptosis

A

leukocytes

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16
Q

5 cardinal signs of inflammation

A

redness
heat
swelling
pain
loss of function

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17
Q

composed of collagen reticular elastic

A

Protein fiber

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18
Q

composition of fiber

A

collagen
reticular fibers
elastic fibers

19
Q

ground susbtances

A

glycoaminoglycans
proteoglycans
multiadhesive glycoproteins

20
Q

most important and abundant fibers of connective tissue

A

collagen

21
Q

Adds soluble galactosine and glucosil sugar

A

glycosilation

22
Q

alpha chains subunits of collagen

A

fibril-forming collagens
network-forming collagens
linking/anchoring collagens

23
Q

found in delicate connective tissue of many organs, notably in the immune system

A

reticular fibers

24
Q

also called elastic lamellae in arteries

A

elastic fibers

25
Q

acts as both a lubricant and a barrier to the penetration of invaders

A

ground substance

26
Q

the watery, largely unstained extracellular material that is more abundant than fibers in some types of connective tissue proper

A

ground susbtance

27
Q

are long polymers of repeating disaccharide units, usually a hexosamine and uronic acid

A

glycosaminodglycans

28
Q

best studies proteoglycans

A

aggrecan

29
Q

key proteoglycan in all basal laminae

A

perlecan

30
Q

consist of a core protein to which are covalently attached various numbers and combinations of the sulfated GAGs

A

proteoglycans

31
Q

4 major GAGs

A

Dermatan sulfate
Chondroitin sulfate
Keratan sulfate
Heparan sulfate

32
Q

large molecules with branched oligosaccharide chains and
allow adhesion of cells to their substrate

A

multiadhesive glycoprotein

33
Q

Water in the ground substance of connective tissue

A

interstitial fluid

34
Q

layer beneath the epithelial lining of many organs and filling
the spaces between fibers of muscle and nerve

A

loose connective tissue

35
Q

generally works to hold organs, anatomic structures, and
tissues in place

A

loose connective tissue

36
Q

a clear predominance of bundled type
I collagen fibers over ground substance

A

dense connective tissue

37
Q

protects organs and strengthens them structurally

A

dense connective tissue

38
Q

bundles of collagen fibers appear randomly interwoven,
with no definite orientation

A

dense irregular connective tissue

39
Q

long, parallel bundles of collagen fibers fill the spaces
between the elongated nuclei of fibrocytes

A

dense regular connective tissue

40
Q

great resistance to prolonged or repeated from the same direction

A

dense regular connective tissue

41
Q

great resistance to prolonged or repeated stresses from the same direction

A

dense regular connective tissue

42
Q

principal component of the fetal umbilical cord, where it is referred to as

A

Wharton’s jelly

43
Q

characterized by abundant fibers of type III collagen

A

reticular connective tissue

44
Q

most abundant in certain lymphoid organs where the fibers form attachment sites for lymphocytes and other immune cells

A

reticular connective tissue

Histology Lecture (8 decks)

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