epithelial tissues Flashcards

1
Q

where are epithelial tissues found?

A

lining all body surfaces (epidermis) and all internal tubes and cavities

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2
Q

what are the functions of epithelial tissue?

A
  • protective barrier (skin) to prevent substances entering/leaving the body (protects against microbial invasion)
  • acts as a continuous boundary between different environments
  • provides opportunity to regulate movement of substances
  • diffusion in lungs and capillaries
  • absorption in the GIT
  • secretion in glands/ ducts
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3
Q

what is the general arrangement of epithelia?

A

continuous sheet of tightly bound cells with lateral surfaces adhered to each other

  • epithelial cells are polarised along the apical/basal axis
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4
Q

what is a tight junction?

A
  • epithelial cells create an impermeable seal between adjacent cells to prevent liquid escaping
  • this prevents water passage and allows a layer of cells to act as an impermeable barrier
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5
Q

what is an example of a tight junction location?

A

epithelium lining the bladder to prevent urine leaking into the extracellular space

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6
Q

what are desmosomes?

A

strong adhering junctions between membranes of adjacent cells, anchoring them together
- they ensure epithelial tissues can stretch while remaining in contact

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7
Q

what are the three ways in which epithelial tissue structure can differ?

A
  • shape
  • number of cell layers
  • apical specialisations
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8
Q

what are the different shapes of epithelial cells?

A
  • squamous
  • cuboidal
  • columnar
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9
Q

what are the names for the different number of cell layers in epithelium?

A
  • simple- single layer of cells- selective diffusion/secretion/absorption
  • stratified- 2 or more layers of cells
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10
Q

what are the apical specialisations of epithelial cells?

A
  • microvilli
  • cilia
  • keratin
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11
Q

what do microvilli do to epithelial cells?

A

increase the apical surface layer

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12
Q

what do cilia do to epithelial cells?

A

assist the movement of particular matter

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13
Q

what does keratin do to epithelial cells?

A

adds a strong protective apical layer

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14
Q

what is the function of simple squamous epithelia

A

lines the surfaces involved in passive diffusion

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15
Q

where is simple squamous epithelia located?

A

in the lungs (alveoli) and capillaries (where its called endothelium)

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16
Q

what is the function of simple columnar epithelium?

A

lines small ducts and tubules involved in absorption and secretion

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17
Q

where is simple cuboidal epithelium found?

A

renal tubes and small ducts of salivary glands

18
Q

what is the function of simple columnar epithelium?

A

lines absorptive surfaces

19
Q

where is simple columnar epithelium located?

A

small intestine

20
Q

what is the function of ciliated simple columnar epithelium?

A

transports ovum from ovary to uterus

21
Q

where is ciliated simple columnar epithelium located?

A

the female reproductive tract

22
Q

where is the apical surface?

A
23
Q
A

faces the external surface

24
Q

what is the function of simple ciliated pseudostratified columnar epithelium?

A

propels the surface layer of mucus containing trapped particles towards the pharynx

25
Q

where is ciliated simple pseudo stratified columnar epithelium located?

A

airways of the respiratory system

26
Q

what does pseudo stratified mean?

A

the nuclei of the cells are at random locations within the cell giving the false impression that there is multiple layers

27
Q

what are goblet cells?

A

modified columnar epithelial cells which synthesis and secrete mucus

28
Q

where are goblet cells found?

A

scattered throughout simple columnar epithelium- repertory/gastrointestinal

29
Q

what is the function of stratified cuboidal epithelium?

A

secretory

30
Q

where is stratified cuboidal epithelium located?

A

it is rare- located in some secretory ducts

31
Q

what is the function of stratified columnar epithelium?

A

secretory and protective

32
Q

where is stratified columnar epithelium located?

A

it is rare- in the male urethra and lining and in some glands

33
Q

describe stratified squamous epithelia

A
  • gives protection from mechanical abrasion
  • cells mature from basal layer from dividing stem cells
  • cells migrate to the apical surface layer
  • the cells appear cuboidal at the basal layer but are just really active, they are squashed into their known squamous shape as they migrate
34
Q

where is stratified squamous epithelium located?

A

the epidermis and oral cavity

35
Q

what are the two specialisations that stratified squamous epithelium can be?

A

keratinised or non-keratinised

36
Q

where does keratin form on epithelium?

A

the apical surface

37
Q

what is the function of keratin

A

enhances resistance to physical stress
- keratin is non living (no nuclei)

38
Q

where are keratinised epithelium found?

A

protected surfaces eg epidermis

39
Q

what is transitional epithelium?

A
  • epithelium which allows for expansion and stretch
  • found ONLY in the bladder
40
Q

how does ulceration occur?

A

when there is a break in continuity of epithelium

41
Q

what causes oral squamous cell carcinoma?

A

dysplastic epithelial cells proliferating in an uncontrollable manner, which destroy and invade adjacent tissues