Epithelial Tissue Flashcards
afferent
towards
efferent
away
acidophilic
structures that stain with acid such as eosin (aka eosinophilic)
basophilic
structures that stain with basic dyes such as hematoxylin
Periodic acid-schiff (PAS)
stains polysaccharides
Immunofluorescence imaging
Decorate component with an antibody that has a fluorescent label to it
endothelium
simple squamous epithelium lining of blood vessels
mesothelium
outside wall of organs
Where does epithelial tissue get its nutrients from?
Epithelial tissue is AVASCULAR, and gets its nutrients from connective tissue
apical
side facing exterior surface (lumen or outside)
basal
facing basal lamina, anchoring cell to connective tissue
microvilli
apical projections that increase surface area of the cell
actin filaments
located in gut and kidney
cilia
important for cell movement
microtubule (tubulin) filaments that come from special organizing centers known as basal bodies
organization known as 9+2
Zonula occludens (tight junctions)
prevents the lateral movement between cells and prevents the mixing of apical and plasma membrane lipids and proteins
SELECTIVE passage of substances
*ONLY FOUND IN EPITHELIUM
zonula adherens (cadherans)
connects actin filament bundle in one cell to the next
calcium mediated
macula adherans (desmosome)
interact with intermediate filaments to form desmosome - majoring anchoring cell to cell junction used to withstand mechanical stress
have adhesion molecules called desmogleins
gap junction
direct passage of signaling molecules from one cell to another
basement membrane
composed of basal lamina and reticular lamina
basal lamina
lamina lucida
lamina densa
Type IV Collagen
laminin
Proteoglycans
reticular lamina
reticular fibers (Type III Colagen)
serosa
mesothelium plus underlining connective tissue
transitional epithelium
dome shaped epithelial cells facing the lumen
only found in bladder and ureters
allows for expansion
basal bodies
where microtubules grow out of
stereocilia
elongated microvilli
hemidesmosome
integrin links cell to basal lamina
tight anchoring to the underlying connective tissue via the basement membrane
made of intermediate filaments
crypts
little crevices going into connective tissue region (protected) where stem cells are kept to regenerate
merocrine
normal exocytosis
apocrine
a material (like a lipid product) is released from cytoplasm to extracellular space by taking plasma membrane with it
holocrine
cells rupture and entire cytoplasmic material is released
serous secretion
watery, non-glycosylated proteins
HE stain
round nuclei
mucus secretion
highly glycosylated (sugars) proteins
PAS stain
flat nuclei
epithelial dyspolasia
abnormality in maturation of cells within a tissue
adenoma
a benign epithelial tumor having a glandular origin and structure
adenocarcinoma
malignant tumor originating in glandular epithelium
closely apposed
cells close to each other
selective barrier
epithelial cells form a selective barrier between underlying connective tissue and the outside environment
facilitates or inhibits the passing of certain materials
Is epithelial tissue vascular?
No! epithelial tissue is AVASCULAR!
where are stereocilia located?
inner ear
male reproductive system
primary cilia
present in almost all cells
function as sensory antennae
motile cilia
most commonly found in epithelial cells
function in transporting secretions, proteins and foreign bodies
also present on sperm cells
terminal web
where actin filaments anchor in microvilli
what are occluding (tight) junctions composed of
proteins:
occludins,
claudins,
JAM (junction adhesion molecules)
heterotypic binding
when binding occurs between different types of CAM
homotypic binding
when binding occurs between same type of CAM
what are zonula adherens composed of?
cadherins and actin
