Epithelial Tissue Flashcards

1
Q

Tight Junctions

A

Impermable junctions that prevent molecules from passing through the intercellular space

Ex: Blood-Brain barrier

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2
Q

Desmosomes

A

Anchoring junctions bind adjacent cells together like a molecular “Velcro” and help form an internal tension-reducing network of fibers

Composed of Cadherin (Linker proteins), Plaque, and Keratine (intermediate filament)

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3
Q

Gap Junction

A

Connexon proteins allow ions and small molecules to pass for intercellular comunication

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4
Q

Which Intercellular junction is most likely to be found on a horizontal structure? Vertical structure?

A

Horizontal: Gap Junction
Vertical: Desmosomes

Gap on the Horizon, Spiders on a String

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5
Q

Apical Surface

A

Upper Free; exposed to exterior of cavity

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6
Q

Basal Surface

A

Lower attached;

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7
Q

Stages of Tissue Repair

A
  1. Inflammation Stage
  2. Proliferation Stage
  3. Regeneration Stage
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8
Q

Describe the Inflammatory stage in Tissue Repair

A
  • Severed blood vessels bleed
  • Inflammatory chemicals are released
  • Local blood vessels become more permeable, allowing WBC, Fluid, Clotting proteins, and other plasma proteins to seep into the injured areas
  • Clotting occurs; surface dries and forms a scab
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9
Q

Describe what happens during the Proliferation Stage of Tissue Repair

A
  • The clot replaced by granulation tissue, which restores the vascular supply
  • Fibroblast produce collagen fibers that bridge the gap
  • Macrophages phagocytize dead and dying cells and other debris
  • Surface epithelial cells multiply over the granulation tissue
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10
Q

Describe what happens during the Regeneration Stage of Tissue Repair.

A
  • The fibrosed area matures and contracts; the epithelium thickens
  • A fully regenerated epithelium with an underlying are of scar tissue
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11
Q

7 Epithelial Tissues

A
  1. Simple columnar
  2. Ciliated pseudostratified columnar with goblet cells
  3. Simple cuboidal
  4. Transitional
  5. Simple squamous
  6. Stratified squamous
    Keratinizing stratified squamous
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12
Q

Simple Columnar E.T.

A

Singe layer of tall cells with round to oval nuclei; may have contain microvilli and/or goblet cells

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13
Q

What is the Function of Simple Columnar?

A

Absorption; Secretion of mucus, enzymes, and other substances

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14
Q

Where are Simple Columnar E.T. generally located?

A

Nonciliated types: lines most of the digestive tract (stomach to rectum), gallbladder, and excretory ducts of some glands

Ciliated types: line small bronchi, uterine tubes and some regions of the uterus

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15
Q

Pseudostratified Columnar E.T.

A

Single layer of cells of differing heights, some not reaching the free surface; nuclei seem at different levels; may contain mucus-secreting cells and bear cilia

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16
Q

What is the function of Pseudostratified Columnar E.T.?

A

Secrete substances, particularly mucus; propulsion of mucus by ciliary action

17
Q

Where are Pseudostratified Columnar E.T. Generally located?

A

Nonciliated type: in male’s sperm-carrying ducts and ducts of large glands
Ciliated types: Line the trachea, most of the upper respiratory tract

18
Q

Simple Cuboidal E.T.

A

Single layer of cube-like cells with large, spherical central nuclei.

19
Q

What is the function of Simple Cuboidal E.T.?

A

Secretion and absorption

20
Q

Where are Simple Cuboidal E.T. generally located?

A

Kidney tubules; ducts and secretory portions of small glands; ovary surface

21
Q

Transitional E.T.

A

Resembles both stratified squamous and stratified cuboidal; Basal cells cuboidal or columnsar; Surface cells dome shaped or squamous-like, depending on degree of organ stretch

22
Q

What is the function of Transitional E.T.?

A

Stretches readily, permits stored urine to distend urinary organ

23
Q

Where are Transitional E.T. generally found?

A

Lines the ureters, bladder, and part of the urethra

24
Q

Mesothelium (Simple Squamous E.T.)

A

Located: in the mesothelia lining ventral body cavity, endothelia lining heart and blood vessels and portions of kidney tubules, inner lining of the cornea and alveoli of lungs

Function: reduces fiction; controls vessel permeability; performs absorption and secreation

25
Q

Simple Squamous E.T.

A

Single layer of flattened cells with disc-shaped central nuclei and sparse cytoplasm; the simplest of the epithelia

26
Q

What is the Function of Simple Squamous E.T.?

A

Allows materials to pass by diffusion and filtration in sites where protection is not important; Secretes lubrication substances in serosae

27
Q

Where is Simple Squamous generally located?

A

Kidney glomeruil; air sacs of lungs; lining of hearts, blood vessels, and lymphatic vessels; lining of ventral body cavity (serosae)

28
Q

Stratified Squamous E.T,

A

Thich membrane composed of several cell layer; basal cells are cuboidal or columnar and metabolically active; surface cells are flattened (squamous); in the keratinized type, the surface cells are full of keratin and dead; basal cells are active in mitosis and produce the cells of the more superficial layers.

29
Q

What is the function of Stratified Squamous E.T.?

A

Protects underlying tissue in areas subjected to abrasion

30
Q

Where are Stratified Squamous E.T. generally located?

A

Nonkeratinized type forms the moist lining of the esophagus, mouth, and vagina

Keratinized type: forms the epidermis of the skin, a dry membrane

31
Q

Endocrine Glands

A

Ductless glands that internally secrete protein hormones or steroid hormones
ex: blood, Interstitial fluid, lymph