Epithelial Tissue Flashcards
Tight Junctions
Impermable junctions that prevent molecules from passing through the intercellular space
Ex: Blood-Brain barrier
Desmosomes
Anchoring junctions bind adjacent cells together like a molecular “Velcro” and help form an internal tension-reducing network of fibers
Composed of Cadherin (Linker proteins), Plaque, and Keratine (intermediate filament)
Gap Junction
Connexon proteins allow ions and small molecules to pass for intercellular comunication
Which Intercellular junction is most likely to be found on a horizontal structure? Vertical structure?
Horizontal: Gap Junction
Vertical: Desmosomes
Gap on the Horizon, Spiders on a String
Apical Surface
Upper Free; exposed to exterior of cavity
Basal Surface
Lower attached;
Stages of Tissue Repair
- Inflammation Stage
- Proliferation Stage
- Regeneration Stage
Describe the Inflammatory stage in Tissue Repair
- Severed blood vessels bleed
- Inflammatory chemicals are released
- Local blood vessels become more permeable, allowing WBC, Fluid, Clotting proteins, and other plasma proteins to seep into the injured areas
- Clotting occurs; surface dries and forms a scab
Describe what happens during the Proliferation Stage of Tissue Repair
- The clot replaced by granulation tissue, which restores the vascular supply
- Fibroblast produce collagen fibers that bridge the gap
- Macrophages phagocytize dead and dying cells and other debris
- Surface epithelial cells multiply over the granulation tissue
Describe what happens during the Regeneration Stage of Tissue Repair.
- The fibrosed area matures and contracts; the epithelium thickens
- A fully regenerated epithelium with an underlying are of scar tissue
7 Epithelial Tissues
- Simple columnar
- Ciliated pseudostratified columnar with goblet cells
- Simple cuboidal
- Transitional
- Simple squamous
- Stratified squamous
Keratinizing stratified squamous
Simple Columnar E.T.
Singe layer of tall cells with round to oval nuclei; may have contain microvilli and/or goblet cells
What is the Function of Simple Columnar?
Absorption; Secretion of mucus, enzymes, and other substances
Where are Simple Columnar E.T. generally located?
Nonciliated types: lines most of the digestive tract (stomach to rectum), gallbladder, and excretory ducts of some glands
Ciliated types: line small bronchi, uterine tubes and some regions of the uterus
Pseudostratified Columnar E.T.
Single layer of cells of differing heights, some not reaching the free surface; nuclei seem at different levels; may contain mucus-secreting cells and bear cilia