Epilepsy Management

Question 1

Benzo’s used for epilepsy

Answer 1

Diazepam, Lorazepam**, Clonazepam

Question 2

Non benzo used for epilepsy

Answer 2

Acetazolamide

Question 3

Use for Benzo’s

Answer 3

Generalized status epilepticus

Clonazepam - absence of seizures

Question 4

Differences in action time for benzo’s

Answer 4

Lorazepam is more effective and longer acting that diazepam

Question 5

Administration of Benzo’s

Answer 5

IV or rectal gel

Oral for long term use

Question 6

Toxic effect of Benzo’s

Answer 6

Tolerance, Sedation

Question 7

Uses of Acetazolamide for seizures

Answer 7

All types including seizures w/ menses

Question 8

Mechanism of acetazolamide

Answer 8

Inhibits carbonic anhydrase

Question 9

Toxic effects of acetazolamide

Answer 9

causes mild acidosis in brain, bicarbonate ions cannot move out of GABA channels in neurons

Rapid tolerance - seizures return