Epilepsia Flashcards

1
Q

Dosis de carbamazepina

A

2-3 mg/kg día

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2
Q

Niveles sericos de carbamazepina

A

4-12 mcg /dl

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3
Q

Mecanismo de acción de Carbamazepina

A

Inhibición de canales de sodio

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4
Q

Efectos adversos de carbamazepina

A
Náusea y vomito 
Hiponatremia
Leucopenia
Erupción cutánea
Difundían séxual
Sx steven jonson
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5
Q

Mecanismo de acción de fenitoina

A

Inhibición de canales de sodio

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6
Q

Dosis inicial y mantenimiento de fenitoina

A

Inicial: 15 mg/kg dividían en 3 dosis (impregnacion no más de 30 mg/hr)
Mantenimiento: 5 mg/kg

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7
Q

Nivel serico meta de fenitoina

A

10-20 mcg/dl

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8
Q

Efecto adverso de fenitoina

A
1- hiperolasia gingival
2- hirsutismo
3- rash
4- deplesion ácido fólico
5- disminución de densidad en hueso
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9
Q

Dosis de oxcarbamazepina

A

Dosis inicial de 300 a 900 mg por dos semana s
Aumentar de 900 a 3000 mg/ día

O 30 mg/kg

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10
Q

Efectos adversos de oxcarbamazepina

A
Mareo
Cefalea
Somnolencia 
Rash
Vértigo
Ataxia
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11
Q

Mecanismo de acción de etosuximida

A

Inhibición de canales de calcio

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12
Q

Tipo de epilepsia para indicación de etosuximida

A

Crisis de ausencias

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13
Q

Dosis y niveles sericos de etosuximida

A

Dosis 20-40 mg

Nivel serico 40-100 mg /dl

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14
Q

Anticonvulsivos que actúan a nivel de GABA

A

Benzodiazepinas

Fenobarbital

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15
Q

Dosis de fenobarbital como anticonvulsivo y nivel serico

A

1-5 mg/kg/día (60-200 mg/día)

Niveles sericos 10-40 mcg/ml

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16
Q

Dosis de fenobarbital en estatus epiléptico

A

15 mg/kg dosis única