EPIDERMAL TUMORS AND CUTANEOUS CYSTS Flashcards by Sharmaine Lozano

Q

A

Epidermal Nevus

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Q

Hyperkeratosis, acanthosis and Papillomatosis differentials

A

C.A.V.E.S DDx:
Conf. and Retic. papillmatosis
A.Nigricans / Acrochordon / Ac.V. Hopf
Verruca vulgaris
Epidermal nevus
Seborrheic keratosis

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Q

A

Inflammatory Verrucous Epidermal Nevus

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Q

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Nevus sebaceus (of Jadassohn)

*not usually associated with pilosebaceous unit; may have own duct emptying straight from the glands into the epidermis

*NO NESTS OF NEVUS CELLS

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Q

Tumors associated with Nevus sebaceus

A

Trichoblastoma
Syringocystadenoma Papilliferum
Basal cell carcinoma

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Q

A

Seborrheic keratosis

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Q

Types of seborrheic keratosis

A

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Q

A

Keratoacanthoma

*glassy, eosinophilic cytoplasm filled with glycogen

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Actinic Keratosis

*there is SPARING OF ADNEXAL STRUCTURES - that’s why the stratum corneum immediately above the adnexal structures have ORTHOKERATOSIS

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Q

Strawberry pattern seen in dermoscopy of actinic keratosis is attributed to what?

A

Sparing of adnexal structures

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Q

A

Actinic Keratosis

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Q

A

Bowen’s Disease

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Q

What findings differentiates bowen’s from AK?

A

full thickness atypia (sa AK, atypia is on the lower layers of the epidermis)
involvement of pilosebaceous units (spared ang adnexal structures sa AK)

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Q

A

Bowen’s Disease

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Q

DDx for Buckshot scatter

A

Bowen’s disease
Paget’s disease
Melanoma in-situ
Sebaceous carcinoma
Spitz / acral nevus

Q

A

Basal cell carcinoma

Q

Important differentials of BCC

A

trichoepithelioma and trichoblastoma

*both may have papillary mesenchymal bodies

Q

Variants of Basal cell carcinoma

A

Q

Immunostains for BCC

A

BER-EP4
BCL2
CD10
Androgen Receptor

Q

Dermoscopic findings of BCC

A

*Blue-black globules
*Blue-white veil
*Arborization
*Maple-leaf

Q

A

Q

Give examples of immunostains for SCC

A

HMWK (CK5/6)
P63

Q

Origin of cysts with epidermal lining + granular layer

A

Infundibulum

*DDx
EIC, milia, comedonal acne

Q

Cyst with trichilemmal differentiation comes from the _____

A

Isthmus

there is no granular layer because it’s usually associated with abrupt keratinization of eosinophilic keratin within the cyst

Q

If a cyst shows epidermal-lining + Granular layer +Multiple hair fibers in cavity. What is the diagnosis?

A

Q

If a cyst is lined with “crenulations” + Granular layer + Mature sebaceous gland. What is the diagnosis?

A

Q

A

Steatocystoma

shark’s teeth
*note the crenulated eosinophilic lining of the cyst wall

Q

A

Steatocystoma

shark’s teeth
*note the crenulated eosinophilic lining of the cyst wall

Q

Pseudocyst with myxoid accumulation

A

Myxoid cyst

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A