ADNEXAL TUMORS Flashcards
POROID CELLS + EPIDERMAL ATTACHEMENT
Poroma
POROID CELLS + INTRAEPIDERMAL
HIDROACANTHOMA SIMPLEX
POROID CELLS + SMALL DERMAL NODULES
DERMAL DUCT TUMOR
POROID CELLS + LARGE DERMAL NODULE +/- CYSTS
HIDRADENOMA
TADPOLE-SHAPED DUCTS
Derived from the eccrine gland ducts
CYST + DECAPITATION SECRETION
APOCRINE HIDROCYSTOMA
APOCRINE HIDROCYSTOMA
CYST + 2 LAYERS OF CUBOIDAL CELLS + NO DECAPITATION SECRETION
- Opens to surface
- Blue papillary fronds projecting into lumen (clear space)
- Decapitation secretion
- Plasma cells
- BLUE dermal nodule with branching cystic spaces
- Papillary fronds projecting into lumen
- Decapitation secretion
Difference of SYRINGOCYSTADENOMA PAPILLIFERUM from HIDRADENOMA PAPILLIFERUM
SCAP looks like a SLIDE (invagination looks like a playground slide) while HP is maze-like and plasma cells are not seen
JIGSAW PUZZLE
BLUE BALL + PEPPERED BY LYMPHOCYTES
stains for Sialomucin (EMPD)
Alcian blue (pH2.5), Colloidal iron, Mucicarmine, PAS
What is the staining of EXTRAMAMMARY PAGET’S DISEASE for PAS and diastase
- Diastase resistant means they don’t contain any glycogen to be digested by diastase
Stains for EMPD
CAM5.2, EMA, CK7
staining pattern of Primary EMPD
CK 7 (+), CK 20 (-)
Secondary EMPD staining pattern
CK 7 (-), CK 20 (+)
SEBACEOUS GLAND STAINS
LARGE SEBACEOUS GLANDS AROUND A DILATED FOLLICLE
BUMPY (papillomatosis), BALD (loss of hair follicles), BUBBLY (high-lying sebaceous glands), BIG GLANDS (apocrine)
- Increase in basaloid germinative cells
- Sebaceous glands > basaloid cells (<50% basaloid cells)
Organoid tumor - comprises of abnormality in the epidermis, hair follicles, sebaceous glands and sweat glands
Nevus Sebaceus
- Increase in basaloid germinative cells
- Sebaceous glands > basaloid cells (<50% basaloid cells)
- basaloid islands in a jigsaw pattern made up of 2 cell population (pale cells in the center and dark cells at the periphery) with hyaline droplets in the middle of the lobules
CYLINDROMA
- poroid cells in the epidermis which grows down into the epidermis with an epidermal attachment
POROMA
- lobule with a predominance of basaloid germinative cells and pockets of sebocytes
SEBACEOMA
- papillae covered by 2 layers of cells and inner columnar cell layer with decapitation secretion and an outer myoepithelial layer
- papillae has fibrovascular core lots of PLASMA CELLS
SYRINGOCYSTADENOMA PAPILLIFERUM
