Epidemiology Flashcards
study of occurrence, distribution, control of health & disease
epidemiology
disease occurs randomly, irregularly
sporadic
disease is constantly present, at low levels, in a population
endemic
(malaria: Sub-Saharan Africa)
sudden, unexpected occurrence, localized
outbreak
outbreak affecting a large population
epidemic
global epidemic
pandemic
incidence of a disease
morbidity
incidence of death
mortality
incidence of death among infected individuals
case fatality rate
small mutations in virulence factors (help avoid immune responses)
antigenic
MR= #cases /#ppl in a population
Morbidity rate
MR = #deaths in population/ # people in population
Mortality rate
CFR = # of deaths/ # of confirmed cases
Case Fatality Rate
major change in antigenic character of virulence factor
antigenic shift
cause epidemics & pandemics
shifts
influenza virus has ____ segments (chromosomes)
8
same individual can be co-infected by two different species of the same organims
superinfection
influenza has infection with multiple strains
reassortment of chromosomes
generation of new strains
antigenic shift
source of infectious agent (living or non-living)
reservoir
human source of infection
(has pathogen, but is not sick)
(typhoid mary)
carrier
animal disease that can be transmitted to humans
zoonosis
organism that transmits disease from one host to another (“living disease carriers”)
vector
lyme disease
ticks
plague
fleas
inanimate object, contaminated
fomite
non-living mobile substance
(water, dust particles)
vehicle
infection acquired in the hospital
nosocomial infection
when the patient is exposed to something under medical care
Healthcare associated infections
sexual intercourse; handshakes
direct contact
water glasses & other fomites
indirect contact
sneezes, coughing
airborne droplets
sewage-contaminated water
waterborne (vehicle)
contaminated foods
foodborne (vehicle)
fungal spores
airborne (vehicle)
puncture wound contaminated with soil
soilborne (vehicle)
mites, ticks, mosquitos
anthropods/insects (vector)
T cells help defend you against ______
everything
when the pathogen is too virulent, _____ might die before transmission, or host might not be able to contact other hosts
host
when pathogens emerge, they are typically very ______
virulent
check with CDC for recommendations
vaccination