Enzymes Flashcards
Many enzymes are flexible and change shape when binding their substrates.T/F
True.
What is the important role that enzymes play in allowing life to exist?
Keep chemical reactions from equilibrium, coordinate reaction rates.
What does an enzyme change about a chemical reaction?
Change the kinetics, Ea (decrease), rate of reaction.
Does not change thermodynamics or equilibrium
The active site of an enzyme is a specialized three-dimensional chemical surface. T/F
True
Covalent modification is one type of enzyme regulation. T/F
True
Most enzymes follow the induced-fit model of substrate binding. T/F
True
Enzymes bind to substrates using the phenomenon of molecular recognition. T/F
True
Some enzymes do not yield data to reject the lock-and-key model. T/F
True
The active site of an enzyme contains parts that contribute to substrate binding. T/F
True. (Weak interaction, van der walls.
The active site of an enzyme includes amino acids involved in catalysis. T/F
True. Amino acids= catalytic groups. Catalysis= breaking or making bonds.
The active site of an enzyme can include parts binding to a cofactor or coenzyme. T/F
True.
Transition-state analogs could serve as good drugs for the inhibition of enzyme drug targets. T/F
True. They are strong inhibitor. Penicillin.
Allosteric regulation can involve feedback inhibition. T/F
True. “The catalytic properties of allosteric enzymes can thus be adjusted to meet the immediate needsof a cell.”
The active site of an enzyme is a local structure, made of adjacent amino acids. T/F
True
