Enzymes

Question 1

What do (inorganic) cofactors do?

Answer 1

Help the enzyme and substrate bind together

e.g., chloride ion for amylase

Question 2

What are organic cofactors called?

Answer 2

Coenzymes

Question 3

What do coenzymes do?

Answer 3

Act as carriers for moving chemical groups between different enzymes (continually recycled)
e.g., NAD in respiration & photosynthesis

Question 4

What do prosthetic group do?

Answer 4

Tightly bind to enzyme, allowing them to carry out catalytic function
e.g., Zinc for carbonic anhydrase

Question 5

When does irreversible inhibition occur?

Answer 5

When bonds between inhibitor and enzyme are strong as inhibitor can’t be removed

Question 6

When does reversible inhibition occur?

Answer 6

When bonds between inhibitor and enzyme are weak (H-bond/ ionic) so inhibitor can be removed

Question 7

What’s end-product inhibition?

Answer 7

When enzymes are inhibited by the product of the reaction they catalyse