ENVELOPED DNA VIRUSES Flashcards
Herpes Simplex Virus (HSV)
HSV 1: saliva or direct contact with lesions
HSV 2: sexual contact or transvaginal
HSV-1, HSV-2
Varicella Zoster Virus (VZV)
direct contact w/ vesicular lesions, respiratory droplets, airborne spread of fluid or secretions of respiratory system
varicella/chicken pox,
herpes zoster/shingles
Cytomegalovirus (CMV)
human body fluids, transplacental, organ transplantation
congenital CMV infection
Epstein-Barr Virus (EBV)
contact w/ saliva
infects lymphoid cells (B-lymphocytes), tonsils, spleen, lymph nodes
infectious mononucleosis,
burkitt’s lymphoma,
B-cell lymphomas,
nasopharyngeal carcinoma
Hepatitis B Virus
blood transfusion,
needlestick injury,
sexual contact,
transplacental
HSV-1
Herpes labialis (lips, outer mouth area)
HSV-2
Genital herpes; Neonatal herpes (TORCH)
varicella/chicken pox
Vesicular rash (‘dewdrop on a rose petal appearance’),
begins on trunk spreads to face/extremities (centrifugal),
lesions of different stages,
latent in dorsal root ganglia
herpes zoster/shingles
reactivation of the varicella virus,
inflammation of sensory ganglia,
fluid-filled blisters, pain, and paresthesia
congenital CMV infection
most common intrauterine viral infection, first trimester
microcephaly, seizures, deafness, jaundice, and purpura
infectious mononucleosis
‘kissing disease’
infectious mononucleosis
‘kissing disease’
malignancies
hepatitis B infection
can lead to cirrhosis and hepatocellular carcinoma
jaundice, dark urine, pale feces, and elevate transaminase levels (liver disease)