ENVELOPED DNA VIRUSES

Question 1

Herpes Simplex Virus (HSV)

Answer 1

HSV 1: saliva or direct contact with lesions
HSV 2: sexual contact or transvaginal

HSV-1, HSV-2

Question 2

Varicella Zoster Virus (VZV)

Answer 2

direct contact w/ vesicular lesions, respiratory droplets, airborne spread of fluid or secretions of respiratory system

varicella/chicken pox,
herpes zoster/shingles

Question 3

Cytomegalovirus (CMV)

Answer 3

human body fluids, transplacental, organ transplantation

congenital CMV infection

Question 4

Epstein-Barr Virus (EBV)

Answer 4

contact w/ saliva

infects lymphoid cells (B-lymphocytes), tonsils, spleen, lymph nodes

infectious mononucleosis,
burkitt’s lymphoma,
B-cell lymphomas,
nasopharyngeal carcinoma

Question 5

Hepatitis B Virus

Answer 5

blood transfusion,
needlestick injury,
sexual contact,
transplacental

Question 6

HSV-1

Answer 6

Herpes labialis (lips, outer mouth area)

Question 7

HSV-2

Answer 7

Genital herpes; Neonatal herpes (TORCH)

Question 8

varicella/chicken pox

Answer 8

Vesicular rash (‘dewdrop on a rose petal appearance’),
begins on trunk spreads to face/extremities (centrifugal),
lesions of different stages,
latent in dorsal root ganglia

Question 9

herpes zoster/shingles

Answer 9

reactivation of the varicella virus,
inflammation of sensory ganglia,
fluid-filled blisters, pain, and paresthesia

Question 10

congenital CMV infection

Answer 10

most common intrauterine viral infection, first trimester

microcephaly, seizures, deafness, jaundice, and purpura

Question 11

infectious mononucleosis

Answer 11

‘kissing disease’

Question 12

infectious mononucleosis

Answer 12

‘kissing disease’

malignancies

Question 13

hepatitis B infection

Answer 13

can lead to cirrhosis and hepatocellular carcinoma

jaundice, dark urine, pale feces, and elevate transaminase levels (liver disease)