Enterovirus Flashcards

1
Q

Biología

A
  • Miembros de la familia Picornaviridae
  • Virus de cápside desnuda, ssRNA+
    • Resiste pH <3
    • Su genoma desnudo puede ser infectante
    • RdRp viral
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2
Q

Cuántos serotipos?

A
  • 71 serotipos
    • Poliovirus
    • Coxsackievirus
    • Echovirus
    • Enterovirus
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3
Q

Se unen a receptores de la superfamilia de

A

Inmunoglobulinas

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4
Q

Amplio espectro clínico, aunque la mayoría son

A

Asintomáticos

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5
Q

Inhiben la síntesis de:

A

RNA y proteínas celulares

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6
Q

Patogenia, transmisión:

A

Fecal-oral

- Excreción viral hasta por 30 días

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7
Q

Infectan:

A

vías respiratorias superiores y tubo digestivo

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8
Q

Primera replicación en

A

Mucosa y tejido linfoide

- Diseminación luego de primera viremia

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9
Q

Replicación en órgano:

A

Diana

Segunda viremia y sintomatología

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10
Q

Son liberados por:

A

Lisis celular

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11
Q

Inmunidad mediada por:

A

Anticuerpos

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