ENT: Throat & Salivary Gland Problems Flashcards

1
Q

What is the most common cause of tonsillitis?

State common causes of bacterial tonsillitis

A
  • Tonsillitis most commonly caused by viral infection
  • Can be caused by bacteria:
    • Most common= Streptococcus pyogenes
    • Second most common= Streptococcus pneumoniae
    • Others= Haemophilus influenza, Moraxella catarrhalis, Staphylococcus aureus
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2
Q

Remind yourself of Waldeyer’s ring

A
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3
Q

Describe typical presentation of tonsillitis

A
  • Sore throat
  • Fever (>38)
  • Odynophagia
  • Red inflamed tonsils +/- exudates
  • +/- anterior cervical lymphadenopathy
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4
Q

Outline the Centor criteria

A

Estimates probability that tonsillitis due to bacterial infection and will benefit from abx. Score of 3 or more gives 40-60% probability of bacterial tonsillitis and it is therefore appropriate to give abx.

  • Fever over 38 degrees
  • Tonsillar exudates
  • Absence of cough
  • Tender anterior cervical lymph nodes
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5
Q

Outline the FeverPAIN score

A

Estimates probability that tonsillitis due to bacterial infection and will benefit from abx. Score of 2-3 gives 34-40% probability and a score of 4-5 gives a 62-65% probability of bacterial tonsillitis and it is therefore appropriate to give abx.

  • Fever during previous 24hrs
  • Purulent tonsils
  • Attended within 3 days of onset of symptoms
  • Inflamed tonsils
  • No cough or coryza
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6
Q

Which pts with tonsillitis would you consider admitting?

A

Consider admission if:

  • Immunocompromised
  • Systemically unwell
  • Dehydrated
  • Stridor
  • Respiratory distress
  • Evidence of peritonsillar abscess or cellulitis
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7
Q

Discuss the management of tonsillitis (acute, not asking about management of recurrent)

A
  • Reassurance and self-care advice e.g. simple analgesia, adequate fluid intake, salt water gargling and local anaesthetic throat spray may help pain
  • Safety netting (if not improved after 3 days or fever rises >38.3)
  • Consider antibiotics if Centor ≥3 or FeverPAIN ≥4 or if at high risk of more severe infection (e.g. immunocompromised, young infants, significant comorbidities, hx of rheumatic fever). Can also consider delayted prescription for if symptoms don’t improve in a few days.
    • Phenoxymethylpenicillin for 10 days
    • If penicillin allergic, clarithromycin
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8
Q

State some potential complications of tonsillitis

A
  • Peritonsillar abscess (quinsy)
  • Otitis media
  • Scarlet fever
  • Rheumatic fever
  • Post-streptococcal glomerulonephritis
  • Post-streptococcal reactive arthritis
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9
Q

Discuss the SIGN guidelines for tonsillectomy

A
  • Bases on number of epsiodes:
    • ≥ 7 in 1 year
    • ≥ 5 per year for 2 years
    • ≥ 3 per year for 3 years
  • Recurrent tonsillar abscesses (≥ 2 episodes)
  • Enlarged tonsils causing difficulty breathing, swallowing or snoring (in children often do adenotonsillectomy for this)
  • Recurrent febrile convulsions secondary to episodes of tonsillitis
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10
Q

Tonsillectomy is usually done as a day case procedure; true or false?

A

Yes, performed under GA as a day case; after period of observation, in which pt has eaten and drank, can usually go home (unless comorbidities, significant sleep apnoea, intra-operative complications etc…)

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11
Q

State some potential complications of tonsillectomy

A
  • Sore throat where the tonsillar tissue has been removed (this can last 2 weeks)
  • Damage to teeth
  • Infection
  • Post-tonsillectomy bleeding
  • Risks associated with a general anaesthetic

**Remember, pts who had tonsillectomy can still get sore throat from other causes after operation

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12
Q

In surgery, what is meant by a primary haemorrhage and what is meant by a secondary haemorrhage?

A
  • Primary: within first 24hrs
  • Secondary: after first 24hrs
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13
Q

Post-tonsillectomy bleeding can be severe, and in rare cases, life threatening; true or false?

A

True; can result in aspiration of blood

Significant bleeding occurs in up to 5%

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14
Q

Discuss the management of post-tonsillectomy bleeding (include immediate & definitive)

A

Immediate

As with any acutely unwell/deteriorating pt do A-E along with:

  • Calling ENT registrar early
  • Keep pt calm & sit them up encouraging them to spit blood out rather than swallowing
  • IV access & take bloods (FBC, clotting screen, G&S and crossmatch)
  • Make them NBM (in case anaesthetic & operation needed)
  • Analgesia
  • Ice pack for back of neck
  • IV fluids (resuscitation or maintenance) if required
  • If severe bleeding or airway compromise, call an anaesthetist as intubation may be required
  • If severe, alert emergency theatre/anaesthetist that the patient may need an urgent arrest of post-tonsillectomy bleed

More definitive

Going back to theatre is the definitive option, however can try the following for less severe bleeds beforehand:

  • Hydrogen peroxide gargle
  • Adrenalin soaked swab applied topically

Pts presenting with post-tonsillectomy bleed, even if not large, most likely admitted for observation

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15
Q

What is quinsy (peritonsillar abscess)?

A

Peritonsillar abscess is a complication of acute tonsillitis, where a collection of pus forms in the peritonsillar space. This pushes the affected tonsil inferomedially into the oropharyngeal space.

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16
Q

Who does quinsy occur in (age)?

A

Unlike tonsillitis, which is much more common in children, quinsy can occur just as frequently in teenagers & adults

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17
Q

What is the most common causative organism of quinsy?

A
  • Streptococcus pyogenes
  • Others: Staphylococcus aureus, Haemophilus influenza
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18
Q

Describe typical presentation of quinsy

A

Patients present with similar symptoms to tonsillitis:

  • Sore throat
  • Painful swallowing
  • Fever
  • Neck pain
  • Referred ear pain
  • Swollen tender lymph nodes

Additional symptoms that can indicate a peritonsillar abscess include:

  • Trismus (pt unable to open their mouth)
  • Hot potato voice (change in voice due to the pharyngeal swelling)
  • Swelling and erythema in the area beside the tonsils
  • Uvula deviation
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19
Q

Discuss the management of quinsy

A

Refer to ENT for assessment & management:

  • Aspiration or incision and drainage
  • IV antibiotics (e.g. co-amoxiclav)
  • Some surgeons also give single dose of dexamethasone

Not all patients need to be admitted:

  • A good principle: admit anyone unable to swallow enough fluid to stay hydrated (IV access, fluids, blood etc…)
  • Patients with a peritonsillar abscess can be discharged after drainage, some intravenous antibiotics and a few hours’ observation if they are well and able to swallow

Other aspects of management:

  • Analgesia (paracetamol, ibuprofen, topical spray)
  • Advise to sleep upright if stertor
  • Consider tonsillectomy (see previous FC)
20
Q

What is obstructive sleep apnoea?

A

Intermittent collapse of pharyngeal airway during sleep causing apnoeic episodes

21
Q

State risk factors for OSA

A
  • Middle aged
  • Male
  • Obesity
  • Alcohol
  • Smoking
  • Macroglossia (i.e. in acromegaly, hypothyroidism)
  • Marfan’s syndrome
22
Q

State some features of OSA

A
  • Episodes of apnoea (reported by partner)
  • Snoring
  • Morning headache
  • Daytime sleepiness/waking up unrefreshed
  • Concentration problems

Severe cases can cause hypertension, heart failure and increased risk of MI and stroke

23
Q

What can be used to assess symptoms of sleepiness associated with OSA?

A

Epworth Sleepiness Scale

24
Q

What questionnaire can be used to classify anaesthetic risk in pts with OSA?

A

STOP-Bang

25
Q

Discuss the management of OSA

A

Pts with suspected OSA require referral to ENT or specialist sleep clinic to perform sleep studies/polysomnography. Management includes:

  • Correcting any reversible risk factors (e.g. stop smoking, stop drinking alcohol, lose weight)
  • Intra-oral devices/mandibular advancement devices
  • Moderate-severe: CPAP
  • Surgery to reconstruct soft palate and jaw (e.g. uvulopalatopharyngoplasty)
  • Informing DVLA

**If can’t do polysomnography can do overnight pulse oximetry

26
Q

State some potential complications of OSA

A
  • Compensated respiratory acidosis
  • Cardiovascular disease
    • Hypertension
    • MI
    • Heart failure
  • Cognitive dysfunction
  • Daytime somnolence
  • Depression
27
Q

What happens to BP with every arousal in OSA?

What happens to daytime BP in OSA?

A
  • With every arousal there is rise in BP (often over 50mmHg)
  • Rise in daytime BP
28
Q

Discuss the pathophysiology of OSA

A
  • When you sleep all muscles relax (including pharyngeal dilators which are responsible for airway patency)
  • Since pharyngeal dilators relax, some loss of tone and hence narrowing is normal in sleep
  • Excessive narrowing occurs in OSA and this may be due to:
    • An already small pharyngeal size undergoing normal degree of muscle relaxation
      • External pressure from increased neck fat or muscle bulk
      • Large tonsils
      • Craniofacial abnormalities
    • Excessive narrowing of normal pharyngeal size
      • Neuromuscular disease with pharyngeal involvement e.g. MND, stroke
      • Muscle relaxants e.g. alcohol, sedatives
      • Increasing age
29
Q

For glossitis, discuss:

  • What it is
  • Appearance
  • Causes
  • Management
A
  • Inflammation of tongue
  • Erythematous, swollen tongue with smooth appearance due to atrophy of papillae
  • Causes:
    • Iron deficiency anaemia
    • B12 deficiency
    • Folate deficiency
    • Coeliac disease
    • Injury or irritant exposure
  • Management: treat underlying cause
30
Q

For angioedema, discuss:

  • What it is
  • Appearance
  • Causes (top 3)
A
  • Fluid accumulation in deep dermis and subcutaneous tissue; can affect limbs, face, lips, tongue etc…
  • Swollen tissue
  • Causes:
    • Allergic reaction
    • ACE inhibitors
    • C1 esterase inhibitor deficiency (hereditary angioedema)
31
Q

For oral candidiasis, discuss:

  • What it is
  • Appearance
  • Risk factors
  • Management
A
  • Oral thrush= overgrowth of candida (usually candida albicans) in mouth
  • White spots or patches on tongue that can be scraped off
  • Risk factors:
    • Inhaled corticosteroids
    • Antibiotics
    • Diabetes
    • Immunodeficiency e.g. HIV
    • Smoking
  • Management:
    • Miconazole gel
    • Nystatin suspension
    • Fluconazole tablets (severe or recurrent)
32
Q

For geographic tongue, discuss:

  • What it is & appearance
  • Causes
  • Management
A
  • Inflammatory condition where there are irregularly shaped patches of lost epithelium and papillae (resembling a map with countries and oceans). Tends to relapse and remit
  • Cause is unknown but can be related to:
    • Stress
    • Mental illness
    • Psoriasis
    • Atopy
    • Diabetes
  • Benign with no harmful effects so doesn’t usually require treatment. Symptoms like burning or discomfort can be treated with topical steroids or antihistamines
33
Q

For strawberry tongue, discuss:

  • What it is
  • Appearance
  • Causes (2 key ones)
A
  • Tongue is erythematous, swollen and papillae become enlarged, white & prominent
  • Causes:
    • Scarlet fever
    • Kawasaki disease
34
Q

For black hairy tongue, discuss:

  • What it is
  • Appearance
  • Cause
  • Management
A
  • Condition due to decreased shedding/desquamation of keratin from tongue’s surface
  • Papillae elongate, so look like hairs. Bacteria & food can cause dark pigmentation of the papillae (but can also be other colours e.g. brown, green etc..)
  • Causes:
    • Dehydration
    • Dry mouth
    • Poor oral hygiene
    • Smoking
    • Head & neck radiation
  • Management:
    • Tongue scraping/swab to exclude candida
    • Adequate hydration
    • Gentle brushing of tongue
    • Stop smoking
35
Q

Discuss, for leukoplakia:

  • What it is/appearance
  • Management
A
  • Pre-cancerous conditions characterised by white patches in mouth (tongue or inside of cheek) that cannot be scraped off
  • Management:
    • NICE CKS says urgent referral to dentist
    • Stop smoking
    • Reduce alcohol intake
    • Monitoring
    • Potentially laser removal or surgical excision
36
Q

For erythroplakia, discuss:

  • What is is/appearance
  • Management
A
  • Pre-cancerous conditions characterised by red patches on tongue (Erythroleukoplakia is a mixture or red & white patches)
  • NICE CKS says urgent referral to dentist
37
Q

For lichen planus, discuss:

  • What it is
  • Appearance on skin
  • Appearance on mucous membranes
  • Management
A
  • Autoimmune condition causing localised chronic inflammation of the skin
  • Appearance on skin: shiny, purplish, flat topped raised areas with white lines across surface (Wickham’s striae)
  • Appearance on mucous membranes (usually mouth):
    • Reticular: net-like web of white lines (Wickham’s striae)
    • Erosive: bright red area
    • Plaques: larger areas of white mucosa
  • Management:
    • Good oral hygiene
    • Stop smoking
    • Topical steroids
38
Q

For gingivitis, discuss:

  • What it is
  • Presentation
  • Risk factors
  • Management
A
  • Inflammation of gums
  • Presentation: swollen gums, bleeding after brushing, painful gums, halitosis
  • Risk factors:
    • Plaque
    • Smoking
    • Diabetes
    • Malnutrition
    • Stress
  • Patients with gingivitis will be managed by a dentist. Treatment involves:
    • Good oral hygiene
    • Stopping smoking
    • Dental hygienist treatment to remove plaque and tartar
    • Chlorhexidine mouth wash
    • Antibiotics for acute necrotising ulcerative gingivitis (e.g., metronidazole)
    • Dental surgery if required
39
Q

For gingival hyperplasia, discuss:

  • What it is
  • Causes
A
  • Abnormal growth of gums
  • Causes:
    • Gingivitis
    • Pregnancy
    • Vitamin C deficiency (scurvy)
    • Acute myeloid leukaemia
    • Medications, particularly calcium channel blockers, phenytoin and ciclosporin
40
Q

For acute necrotizing ulcerative gingivitis, discuss:

  • Presentation
  • Management
A
  • Painful bleeding gums with halitosis & punched out ulcers on gums
  • Management:
    • Refer to dentist and in meantime:
      • Abx (PO metronidazole or amoxicillin 3/7)
      • Chlorhexidine mouthwash
      • Simple analgesia
41
Q

For aphthous ulcers, discuss:

  • Appearance
  • Which diseases can be associated with
  • Management
A
  • Well circumscribed, punched out, white appearance, painful
  • Most have no underlying cause but associated diseases include:
    • IBD
    • Coeliac disease
    • Vit deficiencies (e.g., iron, B12, folate and vitamin D)
    • HIV
    • Behçet disease
  • Mangement:
    • Unexplained ulceration lasting >3/52 refer via 2WW for suspected oral cancer
    • Usually heal in two weeks but can offer:
      • Topical treatments e.g. bonjela, difflam spray, lidocaine
      • Topical steroids if severe e.g. hydrocortisone buccal tablets
42
Q

What duct connects parotid gland with oral cavity?

What duct connects submandibular gland with oral cavity?

A
  • Parotid= Stenson
  • Submandibular= Wharton
43
Q

Which gland is Sialolithiasis most common in?

What features in history would point to Sialolithiasis?

What investigations would you do?

Discuss the management

A
  • Most common in submandibular
  • Colicky pain & post-prandial swelling of gland
  • Sialography (can also do plain x-ray as stones radio-opaque)
  • If impact distally may be able to remove orally but otherwise may require gland excision
  • Potential complication= if become infected → Ludwig’s angina
44
Q

State some causes of hoarseness of voice

A
  • viral illness leading to laryngitis
  • hypothyroidism
  • gastro-oesophageal reflux (causing irritation of throat)
  • laryngeal cancer
  • lung cancer
  • Papilloma’s/polyps on vocal cords
  • growths on vocal cords
    • Nodules (can develop if overuse of voice)
    • Polyps (often associated with smoking)
    • Papilloma’s
  • paralysis of vocal cords (recurrent laryngeal nerve damage)
45
Q

Remind yourself of 2WW pathway for laryngeal cancer

A

Aged 45yrs and over with:

  • Persistent unexplained hoarseness
  • Unexplained lump in neck
46
Q

Discuss the management of intermittent hoarseness of voice

A

In most cases this will settle by itself. To help relieve the symptoms one can:

  • rest the voice (but don’t resort to whispering which can make matters worse).
  • drink plenty of fluids (avoid too many fizzy drinks).
  • avoid alcohol.
  • avoid cigarette smoke.
  • take Antacids e.g Gaviscon if you get a build-up of acid in the throat.
47
Q

What are some options for the management of persistent hoarseness of voice?

A

Depends on underlying cause:

  • Simple advice as on other FC
  • Voice therapy
  • Radiotherapy
  • Surgery