ENT: Neck Problems Flashcards

1
Q

We can describe the location based on neck lump using following terms: anterior triangle, posterior triangle and midline. Remind yourself of borders of anterior triangle

A
  • Superior border: inferior border of mandible
  • Medial border: midline of neck/sagittal line down midline of neck
  • Lateral border: anterior border of SCM
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2
Q

We can describe the location based on neck lump using following terms: anterior triangle, posterior triangle and midline. Remind yourself of borders of the posterior triangle

A
  • Inferior border: middle ⅓ clavicle
  • Posterior border: anterior border of trapezius
  • Anterior: posterior border of SCM
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3
Q

State some potential causes of neck lumps in adults

A
  • Normal structures (e.g., bony prominence)
  • Skin abscess
  • Lymphadenopathy (enlarged lymph nodes)
  • Tumour (e.g., squamous cell carcinoma or sarcoma)
  • Lipoma
  • Goitre (swollen thyroid gland) or thyroid nodules
  • Salivary gland stones or infection
  • Carotid body tumour
  • Haematoma (a collection of blood after trauma)
  • Thyroglossal cysts
  • Branchial cysts
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4
Q

State some potential causes of neck lumps in children

A
  • Cystic hygromas
  • Dermoid cysts
  • Haemangiomas
  • Venous malformation

(obviously can have some of those seen in adults too- these ones are just more likely in children)

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5
Q

State some potential causes of lymphadenopathy

A

Causes can be grouped into:

  • Reactive lymph nodes (e.g., swelling caused by viral upper respiratory tract infections, dental infection or tonsillitis)
  • Infected lymph nodes (e.g., tuberculosis, HIV or infectious mononucleosis)
  • Inflammatory conditions (e.g., systemic lupus erythematosus or sarcoidosis)
  • Malignancy (e.g., lymphoma, leukaemia or metastasis)
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6
Q

For carotid body tumours, discuss:

  • What they are
  • Presentation
  • Treatment
A
  • Excessive growth of glomus cells in carotid body- usually benign (glomus cells are the chemoreceptors, carotid body located just above carotid bifurcation. Also called paragangliomas as groups of glomus cells called paraganglia)
  • Presentation:
    • Slow growing lump in upper anterior triangle
    • Painless
    • Pulsatile
    • Bruit on auscultation
    • Mobile side-to-side but not up & down
    • Can compress surrounding structures (CNIX, CNX, CNXI or CNXII. Pressure on vagus nerve may cause Horner’s)
  • Most treated with surgical removal
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7
Q

For lipomas, discuss:

  • What they are
  • Presentation
  • Management
A
  • Benign tumours of adipose tissue
  • Presentation of lump:
    • Soft
    • Painless
    • Mobile
    • No skin changes
  • Management:
    • Reassure & leave
    • Or surgically remove
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8
Q

For thyroglossal duct cysts, discuss:

  • What they are/how they are formed
  • Presentation
  • Key differential to consider
  • Management
A
  • In fetal development, thyroid gland starts at base of tongue and gradually migrates down the neck to final position in front of trachea beneath larynx; leaves a track behind called ‘thyroglossal duct’. Thyroglossal duct usually disappears but if it persists a fluid-filled cyst can form
  • Presentation:
    • Midline lump
    • Moves up & down when protrude tongue
    • Mobile
    • Non-tender (BUT may be painful if infected)
    • Soft
    • Fluctuant
  • Key differential= ectopic thyroid tissue
  • Management:
    • Usually surgically removed to prevent infections
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9
Q

For branchial cysts, discuss:

  • What they are
  • Presentation
  • Management
A
  • Congenital abnormality in which branchial cleft (most commonly second branchial cleft) fails to form properly during fetal development; this leaves a space surrounded by epithelial tissue and this space fills with fluid.
  • Presentation usually after 10yrs when cyst more noticeable or infected:
    • Lateral, anterior to SCM
    • Soft
    • Cystic/fluctuant
    • Non-tender
    • No movement on swallowing
    • May see fistula
  • Management:
    • Conservative- just monitor
    • Surgical excision (if recurrent infections, causing other problems etc…)
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10
Q

What is Ludwig’s angina?

What are the features?

Discuss the management

A
  • Progressive cellulitis that invades floor of mouth and soft tissues of neck; most cases occur following teeth infections. Is life-threatening as airway obstruction can occur.
  • Features:
    • Neck swelling
    • Dysphagia
    • Fever
  • Management:
    • Airway management
    • IV abx
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11
Q

Summary of neck lumps

A
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12
Q

When examining a neck lump, what should you look and feel for?

A
  • Location (anterior triangle, posterior triangle or midline)
  • Size
  • Shape (oval, round or irregular)
  • Consistency (hard, soft or rubbery)
  • Mobile or tethered to the skin or underlying tissues
  • Skin changes (erythema, tethering or ulceration)
  • Warmth (e.g., infection)
  • Tenderness (e.g., infection)
  • Pulsatile (e.g., carotid body tumours)
  • Movement with swallowing (e.g., thyroid lumps) or sticking their tongue out (e.g., thyroglossal cysts)
  • Transilluminate with light (e.g., cystic hygroma – usually in young children)
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13
Q

State some features of lymphadenopathy that suggest malignancy

A
  • Unexplained (e.g., not associated with an infection)
  • Persistently enlarged (particularly over 3cm in diameter)
  • Abnormal shape (normally oval shaped where the length is more than double the width)
  • Hard or “rubbery”
  • Non-tender
  • Tethered or fixed to the skin or underlying tissues
  • Associated symptoms, such as night sweats, weight loss, fatigue or fevers
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14
Q

Discuss the NICE guidelines for 2WW referrals for neck lumps

A

2WW to head & neck surgeon if:

  • There is an unexplained neck lump in a person aged 45 years or older, or
  • There is a persistent and unexplained neck lump in a person at any age

Referral for ultrasound:

  • In 2 weeks if ≥25yrs and neck lump growing in size
  • In 48hrs if <25yrs and neck lump growing in size
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15
Q

What investigations may be done for neck lumps?

A

Blood tests (the choice of test will depend on the suspected cause):

  • FBC and blood film for leukaemia and infection
  • HIV test
  • Monospot test or EBV antibodies for infectious mononucleosis
  • Thyroid function tests for goitre or thyroid nodules
  • Antinuclear antibodies for systemic lupus erythematosus
  • Lactate dehydrogenase (LDH) is a very non-specific tumour marker for Hodgkin’s lymphoma

Imaging:

  • Ultrasound is often the first-line investigation for neck lumps
  • CT or MRI scans
  • Nuclear medicine scan (e.g., for toxic thyroid nodules or PET scans for metastatic cancer)

Biopsy may be required to gain a tissue sample (histology) to establish the exact cause:

  • Fine needle aspiration cytology – aspirating cells from the lump using a needle
  • Core biopsy – taking a sample of tissue with a thicker needle
  • Incision biopsy – cutting out a tissue sample with a scalpel
  • Removal of the lump – the entire lump can be removed and examined
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16
Q

State the 3 main causes of salivary gland enlargement

A
  • Sialolithiasis (stones blocking drainage through ducts)
  • Infection
  • Tumours (benign or malignant)

*Others, especially for parotid include Sjogren’s, HIV and sarcoidosis

17
Q

Most tumours of salivary glands are benign; true or false?

A

True

  • **80% of salivary gland tumours occur in parotid gland and up to 80% of these are benign*
  • **Most common malignant tumour type in salivary glands is mucoepidermoid carcinoma*
18
Q

We have already said that most tumours of parotid gland are benign. What is the most common type of benign tumour of the parotid gland?

Describe typical presentation

Discuss the management

A
  • Pleomorphic adenoma (proliferation of epithelial & myoepithelial cells of ducts & increase in stromal components)
  • Presentation:
    • 40-60yrs
    • Gradual onset unilateral swelling of parotid gland
    • Painless
    • Usually moveable on examination
  • Management:
    • Surgical excision (2-10% of untreated adenomas turn malignant)
19
Q

State some potential areas for head & neck cancer

A
  • Nasal cavity
  • Paranasal sinuses
  • Mouth
  • Salivary glands
  • Pharynx (throat)
  • Larynx (epiglottis, supraglottis, vocal cords, glottis and subglottis)
20
Q

What type of cancer are most head & neck cancers?

A

Squamous cell carcinoma

21
Q

State some risk factors for head & neck cancer

A
  • Smoking
  • Chewing tobacco
  • Betal nut chewing
  • Alcohol
  • Human papillomavirus (HPV), particularly strain 16
  • Epstein–Barr virus (EBV) infection
22
Q

State some red flags for head & neck cancer

A
  • Lump in the mouth or on the lip
  • Unexplained ulceration in the mouth lasting more than 3 weeks
  • Erythroplakia or erythroleukoplakia
  • Persistent neck lump
  • Unexplained hoarseness of voice
  • Unexplained thyroid lump

*See cancer care for 2WW guidelines

23
Q

Briefly discuss management of head & neck cancer

A

MDT management; specific management dependent on location, stage & pt factors. Treatment may involve:

  • Radiotherapy
  • Chemotherapy
  • Surgery
  • Targeted drugs (e.g. cetuximab is a monoclonal antibody targeting epidermal growth factor receptor)
  • Palliative care
24
Q

SEE CANCER CARE FOR MORE DETAIL ABOUT HEAD & NECK CANCER

A
25
Q

State the 4 types of thyroid cancer- ordering most common to least common

A
  • Papillary (70-80%)
  • Follicular
  • Medullary
  • Anaplastic
26
Q

State some risk factors for thyroid cancer

A
  • Previous H&N radiation
  • Female
  • FH
27
Q

Describe typical presentation of thyroid cancer

A

Most present with asymptomatic thyroid nodule/swelling (could present with compressive symptoms e.g. dysphagia, dyspnoea etc…)

28
Q

Discuss the management of thyroid cancer

A

MDT management. Typical management for papillary & follicular is:

  • Total thyroidectomy
  • Radioiodine (to kill residual cells)
  • Levothyroxine for life
  • Monitor thyroglobulin yearly to detect early recurrent disease