Energy production Flashcards
Where does glycolysis occur?
Cytoplasm of cell
What is rate limiting step glycolysis controlled by?
Phosphofructose kinase
Also regulated ATP and AMP lvls
What is the rate limiting step?
Fructose-6-Phosphate
Fructose-1-6-Bisphosphate
Enzyme- phosphofructokinase
write out both eq
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Outline steps of glycolysis?
Enzymes
Where does the Krebs cycle take place?
Matrix mitochondria
How many ATP can be produced from Kreb’s cycle?
12 ATP one cycle
24- oxidative phosphorylation
Times 2 goes through twice- 24
What activates the Krebs cycle?
High ADP
What occurs if the Krebs cycle is inhibited?
Build up of acetyl coA
Undergo fatty acid synthesis
What inhibits the Kreb cycle?
High levels of ATP, NADH, FADH2
What is rate limiting step controlled by in Krebs cycle?
Isocitrate dehydrogenase
What is the rate limiting step in Krebs?
Isocitrate
Alpha ketoglutarate
Enzyme- isocitrate dehydrogenase
Draw Krebs cycle?
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What is input into Krebs cycle?
1 x Acetyl CoA
Where does the electron transport chain occur?
Inner membrane of mitochondria
What is function of electron transport chain?
Oxidative phosphorylation
What complexes are involved (function)?
Complex 1- remove electrons from NADH
Complex 2- remove electrons from FADH2
- presence co-enzyme Q
(ubiquinone)
Complex 3,4, cytochrome C- donate
electrons to cytochromes contain iron
Oxygen released as result- convert H20
What enzyme helps remove electrons from FADH2?
Co-enzyme Q
(ubiquinone)
What are products of glycolysis?
2 Pyruvate + 2 NADH + 2 H+ + 2 ATP + 2 H2O
What are products of Krebs cycle?
2C, 3 NADH, 1FADH2 and 1 ATP
How many ATP does 1 citric acid cycle produce?
24
3 NADH
1 FADH
GTP
Cycle twice
NADH= 3ATP
FADH= 2
GTP= 1