Endometriosis, PCOS, Infertility

Question 1

What are the most common causes of infertility in women?

Answer 1

PCOS
Endometriosis
Hormonal factors impacting ovulation

Question 2

What is the most common cause of ovarian dysfunction and oocyte abnormalities?

Answer 2

PCOS

Question 3

What is the diagnosis criteria for PCOS?

Answer 3

1. Oligomenorrhea and/or anovulation (ovulatory dysfunction)
2. Clinical or biochemical signs of hyperandrogenism
3. PCOS appearing ovaries on TVUS

Must have 2 out of 3

Question 4

What is the pathophysiology of PCOS?

Answer 4

• Increased LH leads to increased testosterone production
• Decreased FSH production leads to follicular degeneration (disrupted menses) and bilateral cystic ovaries

Question 5

What are the laboratory findings in PCOS?

Answer 5

Increased testosterone (DHEA) and increased LH:FSH ratio > 3:1

Question 6

What is the treatment for PCOS?

Answer 6

• Lifestyle changes (diet, exercise to reduce insulin resistance)
• Combo OCP
• Spironolactone to treat androgen symptoms

Question 7

What are the leading causes of infertility in women?

Answer 7

PCOS
Hormonal factors impacting ovulation
Endometriosis