Endometrial Carcinoma Flashcards

1
Q

most common gynecologic cancer in USA

A

Endometrial ccarcinoma

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2
Q

best prognosis

A

Early diagnosis?

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3
Q

what are risk factors of endometrial carcinoma

A
Obesity
Nulliparity
Late menopause
Adenomatous polyps
Family history
Unopposed estrogen
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4
Q

what are pre-disposing factors f endometrial carcinoma

A

Colon cancer and breast cancer (tamoxifen treatment)

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5
Q

what are decreased risk

A

Oral contraceptives

smoking

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6
Q

what is the most common type of endometrial cacrinoma

A

80% endometrioid type

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7
Q

How many types are there

A

Two

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8
Q

Type One

A

due to long term estrogen therapy (low grade)- progress from endometrial hyperplasia – good prognosis

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9
Q

Type Two

A

atrophic endometrium (high grade)- associated with an atrophic endometrium and have a much poorer prognosis (less common)

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10
Q

when is endometrial carconoma most common

A

Occurs in 6th – 7th decade of life

White

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11
Q

what are clinical symptoms

A

Bleeding
Pain
Uterine distention

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12
Q

what are treatment options

A
Total hysterectomy
Uterus
Ovaries
Tubes
Lymphadenectomy with higher grade cancer
Radiation and chemotherapy
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13
Q

endometrium appearance

A

heterogeneous echo texture with irregular or poorly defined margins, cancer is more likely

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14
Q

what changes within the endometrium may be seen

A

cystic changes

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15
Q

what may also be caused by obstruction of the endometrium canal

A

hydrometra or hematometra

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16
Q

what is indicative of advanced stage disease

A

Enlargement with lobular contour of the uterus and mixed echogenicity is more indicative of an advanced disease stage

17
Q

Stage 1 or 2C

A

Confined to the uterus

18
Q

Stage 3 or 4

A

Extends beyond the uterus
Bladder/rectum infiltration
Adjacent mass
Ureteral obstruction

19
Q

Other imaging

A

MRI/CT
Lymphadenopathy
Metastatic disease (Stage III and IV

20
Q

DD

A

Endometrial hyperplasia
Endometrial polyps
Leiomyoma
Cervical cancer