Endocrinology

Question 1

catecholamines in urine, headaches, hypertension and palpitations

Answer 1

phaeochromocytoma

Question 2

tanned skin without being on holiday

Answer 2

Addison’s

Question 3

increased shoes size, spade hands, wedding ring too tight

Answer 3

acromegaly

Question 4

signs of hyperthyroidism + eye changes, gritty eyes, smooth velvety skin

Answer 4

Graves’ disease

Question 5

moon face, proximal weakness, stretch marks, buffalo hump, abdominal fat

Answer 5

Cushing’s

Question 6

ketones on breath (pear drop smell)

Answer 6

DKA

Question 7

deep laboured breathing (Kussmaul breathing)

Answer 7

metabolic acidosis (esp. DKA)

Question 8

“orphan Annie” nuclei

Answer 8

papillary thyroid cancer

Question 9

bone pain, stones, ado pain, psychiatric problems (bones, stones, groans, moans)

Answer 9

hypercalcaemia –> hyperparathyroidism

Question 10

Psammoma bodies

Answer 10

found in papillary thyroid carcinomas

Question 11

butterfly rash

Answer 11

SLE

Question 12

heat intolerance

palpitations

Answer 12

hyperthyroidism

Question 13

cold intolerance

weight gain

Answer 13

hypothyroidism

Question 14

anosmia and isolated GnRH deficiency

Answer 14

Kallmann’s syndrome

Question 15

Trousseau sign, Chvostek sign and QT prolongation (on ECG)

Answer 15

hypocalcaemia

Question 16

acute management of hypocalcaemia

Answer 16

IV calcium gluconate (10ml of 10% over 10 minutes in 50% dextrose or saline)

Question 17

bradydactyly of the 4th metacarpal

Answer 17

pseudohypoparathyroidism