Endocrinology 5

Question 1

Explain what radioiodine is used for, it’s mechanism of action , pharmacokinetics, and precautions of use.(3)

Answer 1

pg 8

Question 2

Which drug reduces the size and vascularity of the thyroid gland:

A)Propanolol B)Methimazole C)Propylthiouracil D)Lugol’s iodine E) Carbimazole

Answer 2

ANSWER: D

All the others will control thyroid function but the lugol’s iodine, used for 10 days before the operation, will reduce the size and vascularity of the thyroid gland

Question 3

What is a thyroid storm, what are it’s features , what leads to it, how is it resolved(1)

Answer 3

pg 4

Question 4

What are thionamides used for.Describe the mechanism of action , unwanted actions, pharmacokinetics and follow-up action to be used.(8)

Answer 4

pg 4

Question 5

What is the role of beta-blockers in thyrotoxicosis?(1)

Answer 5

pg 7

Question 6

Describe symptoms and natural history of viral thyroiditis(3)

Answer 6

pg 9

Question 7

Giv e a detailed explanation of the signs , symptoms and observations to be made for the two types of hyperthyroidism, explain what leads to the two types of hypothyroidism(7)

Answer 7

pg 1

Question 8

Give a Summary of Hyperthyroidism Symptoms(1)

Answer 8

pg 4

Question 9

Comapre Technetium 99 Pertechnetate to radioiodine , what is used for and results you get for it for the different disease that can affect the thyroid gland(1)

Answer 9

pg 9

Question 10

What are iodine treatment used for.Describe the mechanism of action , unwanted actions, pharmacokinetics and follow-up action to be used.(3)

Answer 10

pg 7

Question 11

Explain the Effects of Thyroxine on the Sympathetic Nervous System(1)

Answer 11

pg 3