Endocrinology 14

Question 1

Explain features of the ob/pb mouse. Explain the significance of leptin and it’s action in human physiology

Question 2

For Ghrelin : Describe structure, release, function , and the factors affecting abundance

Question 3

List the comorbidities that obesity is associated with

Question 4

Describe the thrifty and drifty gene hypotheses

Question 5

Explain the significance of insulin and it’s action in human physiology

Question 6

Explain processes that occur within the hypothalamus for apetite regulation

Question 7

Describe genetics of obesity

Question 8

• Some people are genetically prone to become obese and some are genetically resistant (T/F)

Question 9

What is Saxenda. Explain the features that aid in it’s function.

Question 10

Draw a simple diagram to summarise how the hypothalamus regulates appetite.

Question 11

Explain the how the concentration of PYY changes following injection, and the significance of these changes.

Question 12

For GLP-1 : Describe structure, release and degradation, function , and the factors affecting abundance

Question 13

Describe the structure of where PYY is produced, what other gut hormone is produced here. Explain the function of PYY and factors that control it’s concentration.

Question 14

Give the details of the CNS mutations that affect apetite

Question 15

Summarise features of endocrine function of the GI tract