Endocrine System (Hypothalamus/Postior And Anterior Pituitary Gland) Flashcards
What is the relationship between the hypothalamus and the posterior pituitary gland?
- The posterior pituitary gland is an extension of the neural tissue of the hypothalamus
- they are connected
What neurohormones pass through the posterior pituitary gland?
-vasopressin (ADH) and oxytocin
Where is the neurohormone, vasopressin stored?
- posterior pituitary gland
- used in mammary glands and uterus
Where is the neurohormone, oxytocin stored
- posterior pituitary
- used in kidneys
What is the relationship between the hypothalamus and the anterior pituitary gland?
-not connected directly but through hypothalamic-hypophyseal portal sysetem (portal veins)
Dopamine pathway to targets
Dopamine (hypothalamic) -> Prolactin (anterior pituitary) -> Breast (nonendocrine target)
TRH (thyrotropin releasing hormone) pathway to target
TRH (hypothalamic hormone
->
TSH/thyroid stimulating hormone(anterior pituitary)
->
Thyroid gland, thyroid hormones (endocrine target and hormones)
->
Many tissues ( nonendocrine target)
CRH/corticotropin releasing hormone pathway to target
CRH (hypothalamic)
->
ACTH/adreno-corticotropic hormone (anterior pituitary)
->
Adrenal cortex, cortisol (endocrine targets and hormones)
->
many tissues (nonendocrine targets)
GHRH/growth hormone releasing hormone (stimulates)
Somatostatin (inhibits)
Pathways to target
GHRH or Somatostatin (hypothalamic) -> GH/growth hormone (anterior pituitary) -> Liver, insulin like growth factors (endocrine glands and hormones) -> Many tissues (nonendocrine argots)
GnRH/Gonadtropin releasing hormone pathway to target
GnRH (hypothalamic) -> FSH/follicle stimulating hormone Or LH/ luteinizing hormone (Anterior pituitary) -> Endocrine cells of the gonads, Androgens, estrogens/progesterone ( endocrine targets and hormones) -> Many tissues Or germ cells of the gonads (Nonendocrine targets)