endocrine system Flashcards
Works with the NS to bring about homeostasis.
use specific communication methods and affect specific target organs.
Releases hormones into the bloodstream for distribution throughout the body
Longer periods of effect compared to the N.S.
endocrine system
secretions released into ducts opening onto epithelial surfaces
located within highly vascularized areas to ensure access to the bloodstream
Exocrine glands
: ductless organs that secrete their secretions directly into the blood
located within highly vascularized areas to ensure access to the bloodstream
Endocrine glands
Molecules that have an effect on specific organs.
Only target cells with specific receptors for the hormone respond to that hormone.
Organs, tissues, or cells lacking the specific receptor do not respond to its stimulating effects.
Three types: peptide, steroid, biogenic
hormones
most of our body’s hormones
Formed from chains of a.a., also called protein hormones
Combine with receptors on target cell’s membrane, second messenger system
Ex. growth hormone
Peptide hormones
Derived from cholesterol
Easily diffuses through membranes, form hormone-receptor complex in nucleus and can activate specific genes, transcribe mRNA and make proteins.
Ex. testosterone
Steroid hormones
Small molecules produced by altering the structure of a specific amino acid
Can either bind to receptors on membrane or in cytoplasm
Ex. thyroid hormone
Biogenic amines
A stimulus starts a process, and eventually either the hormone that is secreted or a product of its effects causes the process to slow down or turn off.
Most common control system used by body
Ex. regulation of the blood glucose levels in the body
Negative Feedback Loop
Accelerates the original process, either to ensure that the pathway continues to run or to speed up its activities.
Only a few positive feedback loops occur.
Ex. process of milk release from the mammary glands
positive feedback loop
As the master control center of the endocrine system, oversees most endocrine activity.
Special cells secrete hormones that influence the secretory activity of the ant. pit. (regulatory hormones) releasing hormones (RH) inhibiting hormones (IH)
Directly oversees the stimulation and hormone secretion of the adrenal medulla.
Hypothalamic Control of the Endocrine System
Produces two hormones that are transported to and stored in the posterior pituitary
oxytocin antidiuretic hormone (ADH)
Some endocrine cells are not under direct control of hypothalamus.
Ex. parathyroid hormone
Hypothalamus
Lies inferior to the hypothalamus.
Small, slightly oval gland housed within the sella turcica of the sphenoid bone.
Attached to the infundibulum
Partitioned into anterior and posterior pituitary.
Controlled by regulatory hormones from the hypothalamus. Hormones reach the ant. pit. via hypothalamo-hypophyseal portal system.
Pituitary Gland (Hypophysis)
GH, growth, protein synthesis, lipid mobilization. Target: all cells
Growth hormone
TSH, stim. thyroid gland secretions. Target: thyroid gland
Thyroid-stimulating hormone
ACTH, stim. glucocorticoid secretions. Target: adrenal cortex
Adrenocorticotropic hormone
LH, ovulation, uterine lining, progesterone secretion. Target: ovary cells, uterus
Luteinizing hormone
FSH, estrogen secretion, follicle development. Target: ovary cells
Follicle stimulating hormone:
PRL, milk production. Target: mammary glands
Prolactin
Secretions produced by hypothalamus but released by post. pit
neurosecretions
: ADH, reabsorption of water, increase blood volume. Target: kidney
Antidiuretic hormone
ejection of secretions from targets. Target: ductus deferens, prostate. Female: labor contractions, milk ejection. Target: uterus, mammary gland
Oxytocin