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ex phys II > endocrine system > Flashcards

endocrine system Flashcards

1
Q

endocrine vs paracrine vs autocrine

A
  • endo: acts on any tissue in body
  • para: acts on a tissue in local area
  • auto: acts on tissue that provided secretion
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2
Q

hormone receptor complexes determined by

3 of them

A
  • # of hormones avail
  • # of receptor avail
  • bindgin affinity btwn hormone and receptor
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3
Q

factors determining concentration in plasma

4 of them

A
  • rate of secretion
  • rate of metab, inactivation or exretion of hormone
  • quantity of transport protein
  • changes in plasma volume
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4
Q

what are binding proteins

A

extends half life of hormones

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5
Q

what are steroid hormones

A
  • move freely across lipid membrane of cells

- need to be bound to move around cell

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6
Q

what are amino acid and peptide hormones

A
  • need receptor to cross membrane

- bind to surface receptors and signal 2nd messengers

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7
Q

what does target cell activation depend on?

3 of them

A
  • hormone concen in blood
  • senstivity of receptor for hormone
  • # of target cell receptors
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8
Q

up vs down regulation

A

up: form more receptors
down: caused by long term exposure to hormone
- cell becomes desensitized

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9
Q

fast vs slow acting hormones

A

fast: work quickly during ex to maintain glucose concentration
slow: allow other hormones to exert full effect
- involved in reg of CHO, fat, protein metab

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10
Q

originating gland of GH

what happens to GH during exercise

A

anterior pituitary

-increases w/ ex

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11
Q

stims/inhibitors of GH

A

stim: exercise, sleep, stress, decrease glucose
inhib: insulin like growth factor

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12
Q

GH’s actions

A
  • stim protein synthesis
  • increase glucagon
  • increase fat metab
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13
Q

originating gland of thyroid hormone

what happens to it during exercise

A
  • pituitary gland

- increases

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14
Q

actions of thyroid hormone

A

increased O2 consumption

metabolism of hormones secretd by thyroid gland

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15
Q

stimulators of thyroid hormone

A
  • cold

- increased energy required

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16
Q

originating gland of ACTH

what happens to it during exercise

A
  • pituitary

- doesnt get effected by exercise until 25% of VO2 max

17
Q

stimulators of ACTH

A

-none

secreted in AM

18
Q

actions of ACTH

A
  • regs hormones secreted by adrenal medulla
  • facilitate protein breakdown
  • increase FFA utilization
  • increase gluconeogenesis
19
Q

origainting gland of ADH

what happens to it during exercise

A
  • posterior pituitary

- increase during exercise b/c of sweating

20
Q

stimulators/inhibitors of ADH

A

stim: decrease BP/fluid loss
inhib: fluid overloads

21
Q

actions of ADH

A
  • increase H20 reabsorb

- conservation of fluids

22
Q

originating gland of E/NE (catecholamines)

what happens to them during exercise

A
  • adrenal medulla
  • increase with exercise
  • E @ 75% VO2 max
  • NE @ 50% VO2 max
23
Q

stimulators of catecholamines

A
  • decreased BP and glucose

- too much stress

24
Q

actions of catecholamines

A

increase in:

  • glucogenolysis
  • FFA utilize
  • HR and SV
  • peripheral resistance
25
Q

originating gland of cortisol

what happens to it during exercise

A
  • adrenal cortex

- increase with heavy exercise

26
Q

stimulators of cortisol

A
  • stress

- heavy exercise

27
Q

actions of cortisol

A
  • increase glucogenesis
  • glucose synthesis
  • FFA mobilization
28
Q

originating gland of insulin

what happens to it during exercise?

A
  • pancreas

- decrease with exercise

28
Q

originating gland of insulin

what happens to it during exercise?

A
  • pancreas

- decrease with exercise

29
Q

stimulators of insulin

A
  • increase plasma glucose/amino acid concentration

- decrease E/NE

29
Q

stimulators of insulin

A
  • increase plasma glucose/amino acid concentration

- decrease E/NE

30
Q

insulins actions

A
  • promotes glycogen synthesis

- increase glucose, amino acid, and FFA uptake

30
Q

insulins actions

A
  • promotes glycogen synthesis

- increase glucose, amino acid, and FFA uptake

31
Q

originating gland of glucagon

what happens to it during exercise

A

-pancreas

increase with exercise

31
Q

originating gland of glucagon

what happens to it during exercise

A

-pancreas

increase with exercise

32
Q

stimulators of glucagon

A

decrease plasma glucose

-increase E/NE

32
Q

stimulators of glucagon

A

decrease plasma glucose

-increase E/NE

33
Q

glucagon’s actions

A
  • promotes glycogenolysis
  • increase FFA mobilization
  • gluconeogenesis
33
Q

glucagon’s actions

A
  • promotes glycogenolysis
  • increase FFA mobilization
  • gluconeogenesis

ex phys II (10 decks)

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