Endocrine System Flashcards
What component of the endocrine system secretes their product directly into the blood stream?
Endocrine glabds
Molecules that are
released from one location, move to another
location and produce a response; these
signals are your hormones
Chemical signal
Two types of chemical signal
Intracellular and Intercellular
Chemical signal; produce in one part of a cell
and moves to another part of the same cell;
one cell
Intracellular
Chemical signal; released from one cell and
binds to receptors on another cell; two or
more cells
Intercellular
Enumerate the 5 types of Intercellular signal
Autocrine
Paracrine
Neurotransmitter and neuromodulators
Pheromones
Hormones and neurohormones
Intercellular; released by cells
and a have local effect on the same cell
type
Autocrine
Intercellular; released by cells that affect
other cell types in close proximity
Paracrine
Intercellular; secreted by nerve
cells
Neurotransmitter and
neuromodulators
Intercellular; secreted into the
environment and modify the behavior
and physiology of another individual in
the same species; it has a distinct
permanent smell
Pheromones
Intercellular; secreted into blood and bind to receptor sites
Hormones and neurohormones
Eicosanoids is an example of this
Autocrine and paracrine
Somatostatin is an example of this
Paracrine
Epinephrine and insulin are example of what?
Hormones (and neurohormones)
Epinephrine is also an example of neurotransmitter
a molecule that is released
in one part of the body but regulates
the activity of cells in other parts of the
body.
Hormone
location on a cell where
hormone binds (lock)
Receptor site
a group of cells that respond to
specific hormones
Target tissues
specific hormones bind to specific
receptor sites
Specificity
T or F; Hormones only bind in specific receptor sites
True
Where do hormones bind to lock?
Receptor site
Two types of hormones according to solubility
Water soluble
Lipid hormones/Lipid soluble
What type of hormone does not need a membrane-bound receptor upon entrance to semipermeable membrane?
Lipid soluble
T of F; Lipid-soluble hormones bind to cytoplasmic
receptors and travel to the nucleus or bind to
nuclear receptors.
T
tells the body when
homeostasis is reached (to stimulate or inhibit
hormones)
Negative Feedback
excessive levels of hormones in the
blood stream cause decreased secretion
Negative Feedback
increase the secretion due to low
hormones
Positive Feedback
T or F; Lipid Soluble Hormones bind to Membrane-Bound Receptors
F (They bind to Nuclear Receptors; they don’t need the Membrane-Bound)
What type of hormones need membrane-bound receptors
Water soluble hormones
Called the master gland
Pituitary gland
What controls the pituitary gland
Hypothalamus
What bone protects the pituitary gland
Sphenoid bone
T or F; pineal gland is anterior to pituitary gland
F
2 regions of pituitary gland
Anterior and Posterior
3 ways to secrete hormone
- direct control
- indirect control
- direct release of hormones
Enumerate the hormones secreted by the anterior pituitary gland
Human Growth Hormone (Somatotropin)
Thyroid-stimulating hormone (Thyrotropin)
Luteinizing Hormone
Follicle-stimulating hormone (FSH)
Prolactin
Lab discussion (may additional hormones na nabanggit dun idk)
Adrenocorticotropic Hormone (Corticotropin)
Melanocyte-stimulting Hormone
What hormone stimulates growth of bones, muscles, and organs
Growth Hormone
Target tissues of growth hormone
Most
Target tissue of TSH
Thyroid gland
What hormone regulates thyroid gland secretions
TSH
What happens when there’s too much TSH
Thyroid gland enlarges
What happens when there’s too little TSH
Thyroid gland shrinks
3 gonadotropin hormones for females secreted by the anterior pituitary
LH
FSH
Prolactin
Gonadotropin that promotes ovulation and progesterone
production
LH for females
Gonadotropin that promotes follicle maturation and estrogen
secretion
FSH for females
Gonadotropin that promote milk production
Prolactin
Target tissues of LH in female
Ovaries
Target tissues of FSH in females
Follices in ovaries
LH for males target tissue
Testes
FSH for males target tissues
Seminiferous tubules
Gonadotropin that promotes sperm production and testosterone
LH for males
Gonadotropin that promotes sperm producton
FSH for males
Target tissues of prolactin
Mammary glands and overies
Hormones that posterior pituitaty gland secretes
Oxytocin and Antidiuretic Hormone (ADH) o Vasopressin
Target tissues of ADH
kidneys
Function of ADH
Conserve water
Target tissue of oxytocin
Uterus (ANALAB says it’s uterus and mammary glands)
Hormone that increases uterine contractions during child labor
Oxytocin
Responsible for milk ejection
Oxytocin
Four parts of thyroid gland
Pyramidal lobe of thyroid gland
Right lateral lobe of thyroid gland
Left lateral lobe of thyroid gland
Isthmus of thyroid gland
2 types of hormones secreted by the thyroid gland (ANALAB)
T3 (Triiodothyronine) & T4 (Thyroxine)
Calcitonin
Thyroid gland required ______ to function
Iodine
Regulates metabolic rates and
is needed for growth
Thyroid hormone
Iodine-containing hormone secreted by thyroid follicle
Thyroxine (T4)
Iodine-containing hormone that required conversion
of T4 at target tissues
Triidothyronine
Two common abnormalities relating to thyroid gland
Hypothyroidism
Hyperthyroidism
● Decreased
metabolism
● Weight gain,
reduced
appetite, fatigue
● Low temp. and
pulse
● Dry, cold skin
Hypothyroidsm
What is hypothyroidism called in adults
Myxedema
What is hypothyroidism called in infants
Cretinism
● Increased
metabolism
● Weight loss,
increased
appetite,
nervousness
● Higher temp.
and pulse
● Warm, flushed
skin
Hyperthyroidism
What hormone is secreted when blood Ca2+
levels are high or elevated
Calcitonin
Target tissue of calcitonin
Bone
What hormone is antagonistic to calcitonin
Parathyroid hormone (increases calcium)
What are the target tissues of parathyroid hormone (PTH)
Bone and kidney
regulates blood Ca2+ levels (more
than calcitonin)
stimulates osteoclasts to remove CA from bone
stimulate the kidneys and intestine to absorb
more calcium
PTH
2 regions of adrenal gland
Adrenal Cortex
Adrenal Medulla
Which region of the adrenal gland secretes epinephrine/norepinephrine
Adrenal medulla
Hormone released as part of fight or
flight response
Epinephrine/Norepinephrine
Target tissues of epinephrine/norepinephrine
heart, blood vessels,
liver, fat cell
What hormones are secreted by the adrenal cortex
Mineralocorticoids (Aldosterone)
Glucocorticoids (Cortisol)
Androgens
Hormone directly involved in blood pressure and
volume regulation
Aldosterone
Hormone that causes Na+ and H2O to be
retained and K+ to be secreted
Aldosterone
Target tissue of aldosterone
Kidneys
▪ increases breakdown of fat and
protein for energy uses
▪ reduces inflammatory and
immune responses
Cortisol
Target tissues of cortisol
fat, protein and muscle
Functions:
Males: secondary sexual characteristics
Females: sex drive
Andorgens
Target tissues of Androgens
Most
Hormones that the pancreas secrete
Insulin
Glucagon
Somatostatin
Pancreatic Polypeptide
What cells secrete insulin
Beta cells of Pancreatic Islets
What cells secrete glucagon
Alpha cells of Islets of Langerhans
extra glucose is stored in the
form of ________
glycogen teh
Target tissues of insulin
Liver, skeletal muscle, adipose tissue
When glucose levels are high, what is secreted
Insulin madam
Target tissue of glucagon
Liver
When glucose levels are low, what is secreted
Glucagon
Term for glycogen being broken down
Glycogenolysis eyyy
Type of diabetes mellitus; Insulin dependent; daily injections required
Type I
Type of diabetes mellitus; nsulin independent, often found in obese
people can be treated with diet and treated with
hypoglycemic agents
Type kita EYYYYYYYYYYYY
Type II teh
Hormone that Testes produce
Testosterone
aids in sperm and
reproductive organ development and
function
Testosterone
▪ responsible for adult male
secondary sex characterisics
▪ promotes grown and maturation
of male reproductive system
▪ required for sperm cell
production
Testosterone
Hormones ovaries secrete
Estrogen and progesterone
What specifically produces estrogen
Graafian follices or placenta
stimulates the development of secondary female reproductive organs; prepare the uterus to receive a fertilized egg
Estrogen
What specifically produces progesterone
Corpus luteum (found in ovaries)
acts with estrogen to bring about the menstrual cycle; helps in the implantation of an embryo in the uterus
Progesterone
Located posterior to the sternum; largest in infants and children
Thymus gland
What hormone is secreted by the thymus gland
Thymosin
Target tissues of thymosin
Immune system tissues
Hormone that promotes immune system development and function
Thymosin
What hormone does the pineal gland secretes
Melatonin
Target tissue of melatonin
Hypothalamus
Hormone that plays a role in the onset of puberty controls; cicardian rhythms light affects it functional; sleep wake cyle
Melatonin