endocrine system Flashcards

1
Q

what is the endocrine system made up of

A

endocrine glands

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2
Q

what are endocrine glands

A

ductless glands that secrete hormones into the bloodstream through capillary walls

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3
Q

what are the endocrine glands in the endocrine system

A
  • pituitary gland
  • thyroid gland
  • parathyroid gland
  • adrenal gland
  • pancreas
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4
Q

what are hormones made up of

A
  • proteins
  • fatty acids
  • cholesterols
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5
Q

how are hormones controlled

A

levels of certain chemicals in the blood, so they are only released at appropriate times & amounts

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6
Q

how does the endocrine system work

A

hormones travel around the body sending messages to different target tissues & organs. bind to receptor sites at the target cell and induce changes

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7
Q

features & functions of the hypothalamus

A
  • connected to pituitary gland by specialised vascular system
  • releases hormones which stimulate pituitary gland to release hormones
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8
Q

features & functions of the pituitary gland

A
  • small sized gland located at base of brain
  • divided into anterior and posterior lobes
  • releases various stimulating hormones into bloodstream
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9
Q

anterior pituitary hormones:

A
  • FSH- Follicle stimulating hormone
  • LH - luteinising hormone
  • ACTH - adrenocorticotrophic hormone
  • TSH -thyroid stimulating hormone
  • growth hormone
  • prolactin
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10
Q

posterior pituitary hormones

A
  • oxytocin

- antidiuretic hormone ADH

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11
Q

function of FSH

A
  • stimulates ovary to produce follicles containing egg

- stimulates the testes to produce sperm

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12
Q

name & function of LH or ICSH

A
  • luteinising hormone or interstitial cell stimulating hormone
  • acts in ovary to stimulate ovulation
  • acts on interstitial cells in the testis to stimulate testosterone production
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13
Q

name & function of ACTH

A
  • adrenocorticotrophic hormone

- stimulates adrenal gland to produce hormones that help body cope w/ stress

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14
Q

name & function of TSH

A
  • thyroid stimulating hormone

- stimulates thyroid gland to secrete thyroxine

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15
Q

name & function of GH

A
  • growth hormone

- acts on all tissues of the body, stimulating growth & repair of cells

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16
Q

what can excess or inadequate GH cause

A
  • excess causes gigantism or acromegaly

- inadequate GH causes pituitary dwarfism

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17
Q

function of prolactin

A
  • stimulates mammary glands to develop during pregnancy

- stimulates milk production

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18
Q

function of oxytocin

A
  • targets uterus during birth causes contractions

- acts on mammary gland tissue resulting in milk let down

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19
Q

name & function of ADH

A
  • targets convoluted tubules in the kidneys to reabsorb water, increasing blood volume & pressure
  • reduces amount of water lost from the body
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20
Q

what are feedback mechanisms

A

mechanisms your body has in place to ensure the correct amount of hormone is produced & released

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21
Q

features of positive feedback

A
  • rare & only occur in certain situations

- this loop increase or amplified the effect in the body

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22
Q

features of negative feedback

A

self regulating mechanism to prevent excessive production of hormones

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23
Q

negative feedback mechanisms apply to what hormones?

A
  • oestrogen
  • progesterone
  • testosterone
  • cortisol
  • growth hormone
  • thyroxine
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24
Q

anatomy of the thyroid gland

A
  • located at base of the ventral neck

- has 2 lobes on either due of the trachea near the larynx

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25
Q

function of the thyroid gland

A
  • secretes thyroxine
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26
Q

what is the function of thyroxine

A
  • sets the pace for metabolism in the entire body
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27
Q

what are two conditions of the thyroid gland

A
  • hyperthyroidism - over production of thyroxine

- hypothyroidism - underproduction of thyroxine

28
Q

signs of hyperthyroidism

A
  • hyperactive or restless
  • unkempt fur coats
  • big appetite but losing weight
  • drinking & urinating more than normal
  • can have fast heart tears & high blood pressure
29
Q

signs of hypothyroidism

A
  • sluggish
  • overweight
  • dry coat
  • skin changes
30
Q

what is the parathyroid gland

A

small glands that sit next to the thyroid gland & produce a hormone called parathyroid hormone

31
Q

what is the parathyroid hormone responsible for?

A

calcium & phosphorous regulation in the body

32
Q

when the parathyroid detects a drop in calcium or rise in phosphorous, the parathyroid gland increases the amount of calcium, how does it achieve this?

A
  • reabsorbing calcium from bone
  • increasing calcium absorption in the gut
  • increasing the reabsorption of calcium in the kidney, whilst excreting phosphorous
33
Q

what is hyperparathyroidism

A

a parathyroid disease that causes excessive parathyroid hormone to be excreted

34
Q

what is nutritional secondary hyperparathyroidism

A
  • due to poor nutrition
  • occurs due to low levels of calcium in the diet
  • causes excessive bone resorption
35
Q

what is primary hyperparathyroidism

A

the abnormal enlargement of the parathyroid gland adjacent to the thyroid gland can be seen with cancer

36
Q

what is renal secondary hyperthyroidism

A
  • due to chronic kidney failure

- complex condition occurs when there is reduce filtration through the glomerulus

37
Q

anatomy of the adrenal glands

A
  • cranial to each kidney
  • pea sized in a dog
  • divided into a cortex (outside layer) & medulla (centre)
38
Q

what hormones are produced by the adrenal glands

A
  • glucocorticoids

- mineralocorticoids

39
Q

what is the adrenal cortex responsible for secreting?

A
  • cortisol (stress hormone)

- aldosterone

40
Q

what is the adrenal medulla responsible for

A
  • adrenaline
41
Q

what are corticosteroids important for

A
  • glucose regulation
  • body’s response to stress
  • regulating or decreasing the inflammatory & immune responses
42
Q

features & functions of cortisol

A
  • the stress hormone
  • suppresses immune system
  • ## increases blood glucose when released
43
Q

name of cushings disease

A

hyperadrenocorticism

44
Q

how is cushings disease caused?

A

either tumours in the pituitary gland (too much ACTH) or in the adrenal cortex (too much cortisol), both resulting in excessive cortisol in bloodstream

45
Q

signs of cushings disease

A
  • excessive drinking & urination
  • symmetrical hair loss
  • skin infections
  • pot bellied
46
Q

what hormone does the adrenal cortex produce? ( not cortisol) & what organ does it act on?

A
  • aldosterone
  • acts on kidneys to control sodium & potassium levels
  • regulates water balance & therefore blood pressure
47
Q

what is aldosterone responsible for?

A
  • resorption of sodium
  • excretion of potassium
  • with reabsorption of sodium comes water reabsorption; increasing the circulating blood volume & maintains blood pressure
48
Q

name of addison’s disease

A

hypoadrenocorticism

49
Q

addison’s disease occurs due to what?

A
  1. low cortisol levels

2. low aldosterone levels

50
Q

what does the adrenal medulla produce?

A
  • adrenaline

- noradrenaline

51
Q

why does the adrenal medulla secrete adrenaline

A

stimulation of the nerves of the sympathetic nervous system trigger the adrenal medulla to secrete these hormones

52
Q

adrenaline acts on the body immediately, why?

A

it is responsible for the flight & fight response & therefore survival

53
Q

actions of adrenaline?

A
  • increases heart rate
  • constricts peripheral blood vessels to increase blood pressure ( sending oxygenated blood to just the organs that need it)
  • dilates the airways (opens the airways)
  • dilates pupils (assist with visualisation)
54
Q

hormones produces by the ovaries

A
  • oestrogen

- progesterone

55
Q

how is oestrogen released

A

under the influence of FSH, oestrogen is released from the follicle inside the ovaries

56
Q

oestrogen travels to the pituitary gland & stimulates it to release what?

A

LH ( luteinizing hormone)

57
Q

how is progesterone produced

A

progesterone is released from the corpus luteum formed after the follicle ruptures in the ovary

58
Q

what hormone is produced by the testis

A

testosterone

59
Q

how is testosterone released

A

it’s released by the interstitial cells in the testis under the influence of LH or ICSH

60
Q

what hormones does the kidneys produce

A

erythropoietin

61
Q

what does erythropoietin control?

A

rbc numbers
- kidneys detect when the body had low levels of oxygen & erythropoietin is released into the blood stream & acts bone marrow to stimulate production & release of rbc

62
Q

anatomy of the pancreas

A
  • located adjacent to duodenum
  • L shaped feathery light pink organ
  • has endo & exocrine functions
63
Q

what is the exocrine pancreas function

A
  • produces digestive enzymes (amylase & lipase) which are secreted into a duct that enters the duodenum
64
Q

what is the endocrine pancreas function

A
  • produces insulin; produced by the islet cells scattered in the pancreas
65
Q

how is insulin secreted

A

it’s secreted by small clusters of islet cells that sit in between the exocrine cells that make the digestive enzymes