Endocrine Principles Flashcards
name the three hormones developed from tyrosine
Dopamine
NE and
Epi
and thyroid hormones
describe the production process of peptide/protein hormones
mRNA from nucleus then to ribosomes to be translated then to RER to be modified then into carrier vesicle to golgi in golgi is folded and modified and packaged into excretory vesicles
name the two thyroid hormones
T3
T4
what is another name for T3
triiodothyoninr
what is another name for T4?
tetraiodothronine
what type of hormone do T3/T4 act as
steroid hormones
describe the synthesis of steroid hormones
lipid droplet into cell and goes to mitochondria for P450 enzymes to work on then to SER and released
do steroid or peptide hormones use the SER?
steroid
do steroid or peptide hormones use RER in production?
peptide
what type of hormones are free in blood?
amine and peptide
what type of hormones are bound to proteins in blood?
steroids and thyroid hormones
what is the rule about half life of hormones in blood?
stronger the binding of a carrier protein to a hormone, the slower the clearance and longer the hormone half life
what are three changes seen in increased hormone levels
Target cell desensitization
Down regulation of receptors of another hormone at target cell
up regulation of receptors for another hormone at the target cell
what is an example of increased hormone leading to upregulation of a receptor for a different hormone on the target cell?
hyperthyroidism leads to increased myocyte adrenergic receptors and can cause tachycardia