Endocrine Principles Flashcards

1
Q

name the three hormones developed from tyrosine

A

Dopamine
NE and
Epi
and thyroid hormones

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2
Q

describe the production process of peptide/protein hormones

A
mRNA from nucleus 
then to ribosomes to be translated
then to RER to be modified 
then into carrier vesicle to golgi
in golgi is folded and modified and packaged into excretory vesicles
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3
Q

name the two thyroid hormones

A

T3

T4

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4
Q

what is another name for T3

A

triiodothyoninr

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5
Q

what is another name for T4?

A

tetraiodothronine

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6
Q

what type of hormone do T3/T4 act as

A

steroid hormones

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7
Q

describe the synthesis of steroid hormones

A

lipid droplet into cell and goes to mitochondria for P450 enzymes to work on then to SER and released

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8
Q

do steroid or peptide hormones use the SER?

A

steroid

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9
Q

do steroid or peptide hormones use RER in production?

A

peptide

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10
Q

what type of hormones are free in blood?

A

amine and peptide

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11
Q

what type of hormones are bound to proteins in blood?

A

steroids and thyroid hormones

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12
Q

what is the rule about half life of hormones in blood?

A

stronger the binding of a carrier protein to a hormone, the slower the clearance and longer the hormone half life

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13
Q

what are three changes seen in increased hormone levels

A

Target cell desensitization
Down regulation of receptors of another hormone at target cell
up regulation of receptors for another hormone at the target cell

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14
Q

what is an example of increased hormone leading to upregulation of a receptor for a different hormone on the target cell?

A

hyperthyroidism leads to increased myocyte adrenergic receptors and can cause tachycardia

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