Endo Pathology

Question 1

what is name for benign endocrine neoplasms?

Answer 1

adenomas

Question 2

what is name for malignant endocrine neoplasms?

Answer 2

adenocarcinoma

Question 3

is the ant pit or post pit darker on HE stain?

Answer 3

ant pit is dark and post pit is lighter

Question 4

what is most common cell in ant pit?

Answer 4

somatotrophs

Question 5

name three things the pituitary can impinge on if growing?

Answer 5

optic chiasm
cavernous sinus
CSF

Question 6

if pituitary impinges on optic chiasm, what happens?

Answer 6

bitemporal hemianopia

Question 7

if pituitary impinges on cavernous sinus , what happens?

Answer 7

cranial nerve 3456 palsies

Question 8

are pituitary adenomas usually in ant or post pit?

Answer 8

ant

Question 9

are pituitary adenomas usually monoclonal or multiclonal in hormonal secretion?

Answer 9

monoclonal

Question 10

what are the two size classes of pituitary adenomas?

Answer 10

micro and macro…cutoff is 1 cm

Question 11

what is a craniopharyngioma?

Answer 11

neoplasm in kids that arises from remnants of Rathkes pouch

Question 12

how does craniopharyngioma present?

Answer 12

mass effects

Question 13

what is the characteristic makeup of craniopharyngioma ?

Answer 13

will have solid and cystic components

Question 14

what can be seen on X ray with craniopharyngioma ?

Answer 14

calcifications

Question 15

what vascular issues can lead to pituitary issues?

Answer 15

ischemic necrosis and pituitary apoplexy

Question 16

what causes of ischemic necrosis can affect the pituitary?

Answer 16

postpartum hypotension, DIC, shock, sickle cell

Question 17

does ischemic necrosis lead to hypo or hyperpituitarism?

Answer 17

hypo

Question 18

what is it called when postpartum necrosis of the pituitary happens?

Answer 18

sheehan syndrome

Question 19

what is pituitary apoplexy/

Answer 19

sudden expanding hemorrhage that includes pituitary cells

Question 20

loss of posterior pituitary leads to what issue?

Answer 20

central diabetes insipidus

Question 21

what is the usual cause of posterior pituitary problems?

Answer 21

destruction of the tissue from mass effect or necrosis

Question 22

what mass effect causing things can lead to posterior pituitary issues?

Answer 22

ant pit neoplasms and craniopharyngioma