Endo Pathology Flashcards
what is name for benign endocrine neoplasms?
adenomas
what is name for malignant endocrine neoplasms?
adenocarcinoma
is the ant pit or post pit darker on HE stain?
ant pit is dark and post pit is lighter
what is most common cell in ant pit?
somatotrophs
name three things the pituitary can impinge on if growing?
optic chiasm
cavernous sinus
CSF
if pituitary impinges on optic chiasm, what happens?
bitemporal hemianopia
if pituitary impinges on cavernous sinus , what happens?
cranial nerve 3456 palsies
are pituitary adenomas usually in ant or post pit?
ant
are pituitary adenomas usually monoclonal or multiclonal in hormonal secretion?
monoclonal
what are the two size classes of pituitary adenomas?
micro and macro…cutoff is 1 cm
what is a craniopharyngioma?
neoplasm in kids that arises from remnants of Rathkes pouch
how does craniopharyngioma present?
mass effects
what is the characteristic makeup of craniopharyngioma ?
will have solid and cystic components
what can be seen on X ray with craniopharyngioma ?
calcifications
what vascular issues can lead to pituitary issues?
ischemic necrosis and pituitary apoplexy
what causes of ischemic necrosis can affect the pituitary?
postpartum hypotension, DIC, shock, sickle cell
does ischemic necrosis lead to hypo or hyperpituitarism?
hypo
what is it called when postpartum necrosis of the pituitary happens?
sheehan syndrome
what is pituitary apoplexy/
sudden expanding hemorrhage that includes pituitary cells
loss of posterior pituitary leads to what issue?
central diabetes insipidus
what is the usual cause of posterior pituitary problems?
destruction of the tissue from mass effect or necrosis
what mass effect causing things can lead to posterior pituitary issues?
ant pit neoplasms and craniopharyngioma
