endocrine pancreas Flashcards by Rachel Hall | Brainscape

Q

what are pancreatic islets and what do they secrete?

A

aka islets of langerhans

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Q

what is insulin?
where is it synthesised and process?

A

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Q

what is the structure for insulin?

A

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Q

how is insulin released + in response to?

A

in response to glucose amino acids
via GLUT2 and glucokinase both in liver + pancreas

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Q

insulin release inhibited by?

A

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Q

what is glucokinase?

A

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Q

what is GLUT 2 transporter?

A

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Q

key points of insulin release

A

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Q

what is the PIK3 pathway?

A

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Q

what is the GLUT 4 transporter?

A

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Q

what is the RAS/MAP kinase pathway?

A

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Q

what are the key points of insulin receptors?

A

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Q

what are insulin dependent organs?

A

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Q

what are insulin independent organs?

A

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Q

what are the effects of insulin? glycogen + glucose

A

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Q

what are the effects of insulin? fatty acid + protein

A

Q

what is hormone sensitive lipase?

A

Q

what are the effects of insulin? sodium

A

Q

what is glucagon?

A

Q

what are the effects of glucagon on glycogen + glucose?

A

Q

what are the effects of glucagon on amino acids?

A

Q

what is glucagon receptor ?

A

Q

where are glucagon receptors found?

A

Q

what is hypoglycaemia?

A

Q

what happens in beta blocker overdose

A

Q

what is insulinoma?

A

Q

how do you dx insulinoma?

A

Q

what is glucagonma?

A

Q

what are symptoms of glucagonma?

A

weight loss- liver gluconeogenesis + consumptions of proteins/amino acids

Q

what is dx + tx for glucagonoma?

A

Q

What are MEN syndromes?

A