Endocrine - Disorders of pituiatry/ADH Flashcards
Hyperpituitarism is ____ of the _____ pituitary gland, resulting in over-secretion of _____ or more _____ pituitary hormones.
- Hyperfunction
- Anterior pituitary gland
- One or more anterior pituitary hormones.
2 causes of hyperpituitarism?
- Over-activity
* Adenoma (tumor)
What are 3 findings that can be seen with pituitary tumor?
- Bilateral hemianopia (disturbances of outter half of visual fields of both eyes)
- headaches
- increased ICP
3 Diagnostic tests that are used to visualize pituitary gland in ____?
- X-ray, MRI, CAT SCAN
* Visualize pituitary gland in sella turcica
An example of hyperpituitarism with overproduction of GH. What is this called in children and what is this called in adults?
- Children - gigantism
* Adults - Acromegalia
In gigantism, extreme ____, when over secretion occurs ____epiphyseal closure. What will be seen?
- Extreme Height
- BEFORE epiphyseal closure
- Musculo-skeletal deformities
Acromegalia occurs ______ closure of ______. Enlargement of bones in ____, ___, and ____. What will the face look like? What may this person have difficulty doing?
- AFTER closure of epiphyseal
- Enlarged bones in Skull, Hands, and feet
- Face will be coarse and heavy with heavy lips and large tongue
- Dysphagia - difficulty swallowing
What is a GH inhibitor used to treat Acromegalia? Two other treatments?
- Octreotide
* Irradiation of pituitary and Hypophysectomy
What is a hypophysectomy?
When is this indicated?
- Partial or total removal or the pituitary gland
* pituitary tumors or other cancers
Most common approach to hypophysectomy is ______. Incision is made in _____ and ____, the _____ is entered through ____ and ____ sinuses.
- Transsphenoidal
- incision made in Inner aspect of upper lip and gingival
- Sella turcica is entered through
- Nose and sphenoid sinuses
Postop hypophysectomy, nurse should observe for target ___- _____, such as _____ insufficiency, _____thyroid, and ____ _____.
- Observe for target organ insufficiency.
- Adrenal insufficiency
- Hypothyroid
- Diabetes Insipidus
what two labs/numbers should be monitored for postop hypophysectomy complications? What does these signify?
- I/O - Greater than 800cc/2hours
- Specific gravity less than 1.005
- Diabetes insipidus
Patient positioning after transsphenoidal hypophysectomy? Why?
- Head of bed elevated 30 degrees
* Decreases headache, pressure on sella turcica.
Postop transsphenoidal hypophysectomy, What are 2 signs and symptoms of CSF drainage? What should be done if tested positive for glucose? Nursing interventions?
- Clear drainage from nose or postnasal drip (constant swallowing).
- If positive for glucose, send sample to lab for beta-2-transferrin test
- Elevate head of bed and call doctor.
If pituitary gland is totally removed:
- Client will have permanent _______.
- _____follow-up & hormone replacement of ____, ____, and _____ . Wear ______.
- Permanent diabetes insipidus
- Lifelong hormone replacement - THYROID, CORTISONE, SEX HORMONES
- Wear medic alert bracelet
5 causes of hypopituitarism
- Tumor
- Trauma
- Surgical removal
- Irradiation
- Congenital
Treatment for hypopituitarism?
Fertility? Growth?
- Replacement hormones
- FSH/LH - gonadotrophins
- Somatropin given for dwarfism