Endocrine: Diabetes (Insulin) Flashcards

1
Q

What are the 2 Major Insulin Groups?

A
  • Bolus/Prandial
  • Basal
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2
Q

Describe the two sub-groups of Bolus/Prandial.

A

Rapid Acting:

  • insulin lispro (Humalog®), aspart (Novolog®), glulisine (Apidra®)

Regular/Short Acting:

  • Regular insulin (Humulin R®/Novolin R®)
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3
Q

Describe the two sub-groups of Basal.

A

Intermediate Acting:

  • Neutral Protamine Hagedorn (NPH) insulin (Humulin N®)

Long Acting:

  • insulin glargine (Lantus®)
  • insulin detemir (Levemir®)
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4
Q

S/S of Diabetes Mellitus?

A

BIG THREE: Polyuria, Polydipsia, Polyphagia
- Glycosuria, Unexplained weight loss, Fatigue, Blurred vision

  • Elevated fasting blood glucose (higher than 126 mg/dL)
  • OR
  • hemoglobin A1C (HbA1C) level greater than or equal to 6.5%
  • OR
  • Symptoms of diabetes plus casual plasma glucose level of 200 mg/dL or higher
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5
Q

Diabetes monitoring (glucose levels) nursing considerations?

A
  • Acute monitoring of patient’s current glucose
  • Fasting blood glucose goal for diabetic patients of 70 to 130 mg/dL
  • <70 mg/dL is HYPOGLYCEMIA (dangerous!)
  • Many providers will have hold parameters to not give medications that lower glucose if <100 mg/dL
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6
Q

Diabetes monitoring (hemoglobin A1C levels) nursing considerations?

A
  • Chronic monitoring of patient’s 3-month average
  • Patients with diabetes have a goal A1C of <7
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7
Q

How are Diabetes Type 1 and Type 2 treated?

A

Type 1:

  • Insulin therapy

Type 2:

  • Lifestyle changes (diet, exercise)
  • Oral drug therapy and/or Insulin therapy
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8
Q

What is Insulin used to treat?

A
  • DIABETES =hyperglycemia
    • type I and II diabetes
  • BOLUS/SHORT ACTING insulin for hyperkalemia
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9
Q

What should you assess before giving diabetes medication?

A

Primary/Required: Blood Glucose!

  • Hypoglycemia is defined as <70 mg/dL
  • HARD RULE: Hold if BG<70
  • HOLD Meal insulins if patient is NPO

Secondary:
- Potassium- We check this while patients are on IV DRIPS
- Hemoglobin A1C

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10
Q

How is Insulin administered?

A

Insulin is NOT absorbed orally

  • SUBCUTANEOUS:
    • Most of our insulins are given subcutaneously
  • INTRAVENOUS:
    • Insulin can be given as IV for emergency purposes
    • Rapid insulin as IV push to treat hyperkalemia or critically high glucose
    • Rapid/Regular insulin can be given as a continuous IV infusion for HHS/DKA patients
  • INHALED:
    • There is an insulin inhaler!
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11
Q

What type of insulin is given intravenously?

A

Regular insulin (Humulin R®/Novolin R®)- SC or IV

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12
Q

ALL Insulin adverse effects?

A
  • Hypoglycemia
  • Peak is the most dangerous time
  • Lipo-hypertrophy
  • Hypokalemia
  • Weight Gain
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13
Q

Insulin nursing considerations?

A
  • Before giving insulin (primarily MEAL insulin):
    • Assess current glucose level
    • Can the patient consume food (NPO, N/V)?
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14
Q

What are some early and late signs of Hypoglycemia?

A

If BG< 70 mg/dL

Early Signs:

  • “Hangry” = Confusion, irritability
  • “ Fight or Flight”= tremor, anxious, sweating, palpitations, cold

Late Signs:

  • Hypothermia, seizures
  • Coma and death will occur if not treated
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15
Q

Describe the steps for managing Hypoglycemia.

A
  • Step 1: CONFIRM with a Blood Glucose
    • Hypoglycemia defined as <70 mg/dL
  • Step 2: Manage acutely
    • PATIENT IS ALERT (give 15 grams carbs or juice)
  • PATIENT has decreased LOC (not alert)
    • Give IV dextrose (dextrose=glucose)
    • Or IM Glucagon
  • Step 3: Repeat q15 min until BG> 70
  • Step 4: Order some food for the patient!
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16
Q

Drugs that increase Hypoglycemia risk?

A
  • Combining multiple diabetes medications
  • Beta Blockers (also mask s/s of hypoglycemia)
  • Alcohol
17
Q

Drugs that increase Hyperglycemia risk?

A
  • Corticosteroids
  • Diuretics
18
Q

How should insulin be stored?

A

UNOPENED:

  • Keep UNOPENED insulin in refrigerator to make it last longer and prevent bacterial growth
  • Use normal expiration date on vial

OPENED:

  • Once opened, can keep at room temperature
  • HOWEVER, must discard most insulins after 28 days
19
Q

Describe Clear vs. Cloudy insulin.

A
  • CLEAR- Most insulins are clear
  • CLOUDY- investigate!
    • Could be expired, contaminate growing
    • OR it contains NPH insulin (safe to use)
  • DO NOT ADMINISTER if it is cloudy or has a precipitant except for NPH insulin and any mixed insulins with NPH
20
Q

Which insulins can we mix?

A

Which insulins can we mix?

A) Rapid + NPH
B) Regular/Short + NPH

  • NEVER mix with true long acting (glargine or detemir) and there is NO point in mixing Rapid + Regular
21
Q

How do you mix insulin?

A

Roll vials between hands instead of shaking them to mix suspensions. (NEVER SHAKE INSULIN- You can degrade it.