Endocrine

Question 1

pituitary tumor, parathyroid adenoma, pancreatitc tumor (esp gastrinoma)

Answer 1

MEN 1

Question 2

primary hyperparathyroid, pheochromocytoma, medullary thyroid cancer,

Answer 2

MEN 2A

Question 3

pheochromocytoma, medullary thyroid cancer, marfanoid habitus, mucosal neruomas

Answer 3

MEN 2B/3

Question 4

painful thyroid enlarge after viral illness, transient hyperthyroid, less radioactive iodine uptake, elevated esr

Answer 4

subacute granulomatous thyroiditis

Question 5

histo of subacute granulomatous thyroiditis

Answer 5

inflammatory infiltrate with macrophages and giant cells

Question 6

histo of hashimotos

Answer 6

lymphocytic infiltrates with well-developed germinal centers, Hurthle cells (eosinophillic epithelial cells)

Question 7

histo of extensive fibrosis extending into other tissues beyond the thyroid capsule

Answer 7

Riedel thyroiditis

Question 8

delayed puberty, hypogonadism, and anosmia

Answer 8

Kallman

Question 9

pathophys of Kallman

Answer 9

defective migration of GnRH releasing neurons to hypothalamus

Question 10

pathophys of long term use of corticosteroids

Answer 10

suppress HPA axis, leads to bilateral andrenal atrophy

Question 11

sudden cessation of long term use of corticosteroids can precipitate…

Answer 11

adrenal crisis

Question 12

muscle cramps, perioral paresthesia, hypotension, neuromuscular hyperexcitability

Answer 12

hypocalcemia

Question 13

common cause of acute hypocalcemia

Answer 13

injury to parathyroid glands during thyroid surgery leads to hypoparathyroid

Question 14

urine of SIADH patients

Answer 14

innapropriately concentrated given degree of hyponatremia >100