Endocrine Flashcards
what causes keto acidosis
Type 1 diabetes,
or type 2 with neglect, illness stress
It is from lack of insulin
MEtabolic acidosis 8
HA, hyper k, mm twitching, warm flushed skin, NV, decreased mm tone, decreased reflexes, kussumal
MEtabolic acidosis 8 why?
HA, hyper k, mm twitching, warm flushed skin, NV, decreased mm tone, decreased reflexes, kussumal
DKA
what causes signs and symptoms of DKA
5
Metabolic acidosis, dehydration, glucose. metabolic, hypo electrolytes
What labs would you want for DKA
anion gap, BMP-Glucose,electro,kideney, art gas,BP, Serum osmolality, urine stuff, cbc
Can DKA be outpatient
yes if they do not have an infection and no serious s/s
how do we treat right away for DKA?
O2, then IV- 0.45-0.9 NS, add dextrose if below 250-SLOWWW, short acting insulin, and k+ because of insulin at 0.1 units and increased output, possibly bicarb, Cardiac monitor, labs
What is hyperosmolar hyperglycemia
Its an emergency with 600+ BG levels, and severe osmotic diuresis caused by infection or newly diagnosed DM11
What are we concerned about hypersomolar hyperglycemia
What can that lead to
Hypovolemia, Hypoelectrolytes, dehydration, Hemoconcentraition, renal perfussion, tissue anoxia (Lactic levels increased)
Seizure, shock, coma, death
S/s of hyperos hypergly
Hypovolemia s/s, dehydration s/s, shock s/s, high urine output to low urine output, seizure, high bg, stroke- similarities. LOV issues, s/s of hypoglycemia- mimic alcohol.
Management of Hyperos hypergly
Similar to DKA, more fluid, might need a foley, breath sounds, IV- normal half normal, add dextrose at 250, insulin electrolytes, watch cardiac, renal, Mental status.
What is the number for hypoglycemia
less than 70
s/s for hypoglycemia
what happens if you dont get help?
Shaky, palp, nervous, diaphoretic, hunger pallor
Neuroglycopenia- Diff speaking, visual disturbances, stupor, confusion, coma
loss of c. seizures, coma, death
What is the rule of 15?
and 2 things to remember
2 pharm interventions
take 15g of simple carbs or gels or tabs, check in 15, repeat. If no change in 2-3 times call HCP No foods with fat-slows glucose Don't over do it 20-50ml 50% DEXTROSE Glucogon
To remember about diabetic care
A1c Every 3 months, Stop smoking- circulation, check for dry skin or callus, use lotion but not in-between toes.
causes of SIADH and what is it and more common in
Its over production of ADH
sm lung cancer, brain trauma, brain surg, Drugs, ICP
males
How do we diagnose SIADH 3
High consentrated urine so increased Special gravity, Low serum osmolality, and hypona+
S/s
6 OF SIADH
Low urine output 10/ml.hr or less, increased circulating volume THiRST, Increased GFR, Hypona+ s/s, sudden weight gain without edema,
S/S Of hypona+
mm cramps, irritablity, fatigue, HA, Twitching, mm weak, cerebral edema vomiting, confusion, seizures, coma,
What are we focused on with SIADH how do we do that? 6
Dilutional Na+- Seizure and fall precautions, watch s/s give 3% if supper low very slow too fast causes permanent brain nerve damage
FVOL-Heart and lung sounds, Is and OS, daily weights, BP, fluid restriction maybe 500 skin, rom, loops( watch K)
watching neurofunction
Thirst- Ice chips gum oral care tin drugs
Dont increase ADH- no drugs- vassopressin, DDAVP flat bed
decrease ADH- Vassopressin antag demecylocine
Types of DI and about them
Central- Interference with ADH production tumors, infections, brain surgery
Neph-kidneys wont respond- Lith, renal damage
primary- Thirst issues
Manifestations of di 5 causes with with r/t s/s
polydipsia, polyuria,- 2-20 l a day with low SG
Increased plasma osmolality
Sleepy from nocturia
dehydration-thirst, hypo, tachy, shock
Hyperna+ irritable, mental dullness, coma
DI and three things to watch for one thing to teach
Specific tx for neph and central-
Hyperna+-Watch s/s, hypotonic solutions, dextrose-watch glucose and its diuretic effect.
Increase fluids-DDAVP and aqueous vassopressin
FVD- Thirst- CLor and carban, I and O, Vitals-esspecially volume rt, Specific gravity, daily weights, flushed skin- sign of FVD
Long term mat
Nephro-Fluids and decrease Na+ no hormones, thiazides, indometh-NSAID and increases kid sensitivity.
Explain test for DI
Water deprivation test before test measure body weight, urine osmo, volume, and sg no water for 8-12 hr Give presser Central-increse urine osmo nephro- no increase in urine osmo
What is thyroidtoxicosis
causes
Thyroid storm, hyperthyroidism, emergency,
Infection, trauma, stress, thyroidectomy-#1 from release of hormones when removing it.
Manifestations of thyrotox 7
Severe Hyperthyroid s.s, heart fail, shock, seizure, delirium, coma, ab pain,
Management with thyrotox-
6 with examples.
Agressive tx
Help heart- beta blockers, monitor, VA ECHMO, Balloon pump
Get thyroid hormone decreased- meds- Iodine, RA iodine, PTU drugs, glucosteroids, IV isotonic with Dex, surg if goiter or unresponsive to meds
Watch for complications-DysR, give 02, Watch dehydration and listen to lungs
diet-Increase cals, prots and fiber, no season, no stimulants
tx exo- prevent cornal injury, tears, no salt, increase HOB. tape, dark glasses, tepez drug
REST
S/S of hyperthyroidism
Edema. Increase activity, menstrual issues, decreased libito, decreased firtility. impotence, dyspnea, warm smooth moist skin, thin brittle nails, hair loss, decreased LDL, cardiac changes, clubbing, red palms, premature grey, fine silky hair, vertigo, into to heat, increased temp,
drugs for hyperthyroidism 4 and about them
Antithyroid meds-zoles,
Iodine-not long term just for surg
beta blockers
Radioactive iodine-not for preg, destroys tissue, can cause hypt, radioactive precautions.