Endocarditis Flashcards

1
Q

Infective endocarditis

A
  • Endocardial surface of the heart is infection
  • usually bacterial
  • Valvular damage
  • Subacute (SBE) or acute (ABE)
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2
Q

SBE causes

A
  • Rheumatic fever w/ valve vegetations
  • MVP
  • Calcific aortic stenosis
  • Congenital bicuspid valve
  • Prosthetic valve
  • Cath injury
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3
Q

SBE infection

A
  • Damage to valve endothelium
  • Heart valve vegetation from thrombus = culture for bacteria
  • S. viridians most common
  • Antbx tx for 6 wks
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4
Q

SBE organism interaction

A
  • Organism accerlates platelet aggregation and fibrin deposits
  • “biofilm” for protection
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5
Q

Complications with SBE

A
  • Embolization
  • Valve destruction
  • Conduction defects
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6
Q

SBE presentations

A
  • Night sweats, fever, weight loss, malaise, joint pain
  • Hx valvular disease
  • Hx dental work
  • Heart murmur
  • Conduction defects
  • Splenomegaly, petechia
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7
Q

ABE presentation

A

-Dyspnea/cough/CP, confusion/mental status changes, higher fevers, CHF, marked leukocytosis, sl. incr. ESR, septic arthritis/meningitis

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8
Q

ABE manifestations

A
  • Splinter hemorrhages
  • Lesion at base of 1st finger and great toe
  • Conjunctival petechia
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9
Q

ABE tx

A
  • Antibx 6 weeks
  • Valve replacement
  • No resolution with Abx could be access
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10
Q

Prophylaxis should only be used on highest risk pt

A
  • Prosthetic heart valves
  • Previous endocarditis infx
  • Cyanotic congenital heart disease
  • Surgically constructed systemic pulmonary shunts and conduits
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