Endocarditis Flashcards
most common cause of acute IE?
staph aureus
most common cause subacute IE?
viridans streptococci
what commonly causes IE in patients with prosthetic heart valves?
staph epidermidis
can be days to years after
what are atypical causes of IE?
coxiella burnetti, HACEK bacteria, brucella, fungi
what are the symptoms of subacute IE?
fever
malaise
weight loss
tiredness
dysponoea
clinical signs of IE?
- New/changed heart murmur
- Finger clubbing
- Splinter haemmorrhages
- Splenomegaly
- Roth spots
- Janeway lesions
- Osler nodes
- Microscopic haematuria
what are the timings of taking blood cultures in patients with acute & subacute endocarditis?
acute - 1 hour
subacute- 6 hours
3 cultures taken
what is a feature of HACEK organisms that is an issue?
they very slowly grow, so there can be false negatives/ missed
when is serolgy used?
to test for atypicals if cultures are negative
what is the name of the criteria to rule in/ out IE?
Dukes Criteria
colonoscopy can be given to patients with which bacteria?
patients with strep bovis
What is the empiric treatment for native valve acute Infectious endocarditis?
Flucloxacillin IV
What is the empiric treatment for native valve subacute Infectious endocarditis?
Amoxicillin and Gentamicin IV
What is the empiric treatment for infectious endocarditis in patients with a prosthetic valve?
Vancomycin and Gentamicin IV
add rifampicin PO days 3 to 5
What is the empiric treatment for infectious endocarditis by suspected MRSA?
Vancomycin and Gentamicin IV
add rifampicin PO days 3 to 5