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Clin Med II > Endo Treatment > Flashcards

Endo Treatment Flashcards

1
Q

Treatment for acromegaly

A

tumor resection

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2
Q

Tx for papillary thyroid cancer?

A

surgery then if stage 3 or 4 do radioactive iodine

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3
Q

How do you treat adrenal crisis?

A

hydrocortisone

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4
Q

What is treatment for central diabetes insipidus?

A

Desmopressin

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5
Q

Tx for pheochromocytoma

A

alpha blockade followed by beta blockade to lower BP

then once BP controlled laptoscopic adrenalectomy

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6
Q

Treatment for graves dz

A

Methimazole to stop TH production and then thyroidectomy or radioactive iodine ablation

once thyroid is taken out will need levothyroxine later one because will be hypothyroid

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7
Q

After starting a patient on levothyroxine when should you check their labs?

A

4-6 weeks

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8
Q

Treatment for pregnant patient with Graves disease

A

PTU

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9
Q

Treatment for thyroid storm

A

steroids

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10
Q

What are long acting insulin therapy choices that can be used for basal rate?

A

Glargine or Detemir

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11
Q

What are short acting insulin therapies that can be used for bolus?

A

lispro
aspart
glulisine

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12
Q

Hypothyroidism tx

A

give T4 (body will convert to T3)

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13
Q

Octreotide class

A

Somatostatin analog

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14
Q

Lanreotide class

A

Somatostatin analog

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15
Q

Desmopressin (DDAVP) class

A

Anti-Diuretic Hormone (synthetic)

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16
Q

Spironolactone class

A

Potassium-sparing Diuretics

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17
Q

Eplerenone class

A

Potassium-sparing Diuretics

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18
Q

Levothyroxine class

A

Thyroid Hormone (synthetic)

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19
Q

Methimazole class

A

Thyroid Hormone Synthesis Inhibitor

20
Q

If you have low TOTAL calcium what do you have to make sure to correct?

A

low albumin

21
Q

Diabetes glycemic control targets

A

HbA1C <7%, pre-prandial capillary glucose 80-130, peak post-pranial glucose <180

22
Q

What does U 100 mean?

A

100 units of insulin per mililiter

23
Q

What are the rapid acting insulin drugs?

A

Lispro
Aspart
Glulisine

24
Q

What are the long acting insulin drugs?

A

Glargine
Detemir
Degludec (very long)

25
Q

What are the intermediate acting insulin drugs?

A

NPH

26
Q

How much insulin is required daily?

A

0.6-0.7 units/kg

27
Q

SOA of alpha-Glucosidase inhibitors

A

GI tract dec carb absorption

28
Q

SOA of metformin

A

liver dec glucose production

29
Q

SOA of GLP-1 agonist

and DPP-4 inhibitor

A

GI tract

and increases insulin secretion at pancreas

30
Q

SOA of Sulfonylureas, Meglitinides and Nateglinide

A

Pancreas- increases insulin secretion

31
Q

SOA of Glitazones

A

muscle and fat increases glucose uptake

32
Q

SOA of SGLT2 inhibitor

A

kidney increases glycosuria

33
Q

SE GLP1

A

weight loss

34
Q

SE of insulin

A

wt gain

35
Q

Metformin SE

A

GI SE

contraind w/ GFR <30

36
Q

DPP4 SE

A

risk of acute pancreatitis

renal dose adj-for Januvia®, Nesina®, Onglyza®

37
Q

SGLT-2 Inhibitors renal considerations

A

Decreased efficacy as GFR

decreases, not recommended with GFR <30-60

38
Q

SGLT-2 Inhibitors SE

A

Risk of DKA (class effect)
Genitourinary infections
Risk of volume depletion
Increased LDL cholesterol

39
Q

Pioglitazone BBW

A

CHF

also has risk of bone fx and bladder ca

40
Q

What oral agent should you avoid in patients with high HbA1C?

A

DPP-4 inhibitor

41
Q

What are the injectables for DM treatment?

A

GLP1 RA and insulin

42
Q

GLP1 RA SE

A

BBW medullary thyroid ca

GI SE

43
Q

How should you change insulin dose as GFR decreases?

A

Lower insulin doses as GFR

decreases due to increased risk of hypoglycemia

44
Q

Tx of primary hyperparathyroidism

A

surgery

45
Q

What do you need to warn pts about when taking Levothyroxine

A

Do not take within 1 hr of food or 4 hrs of calcium or iron

Clin Med II (19 decks)

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