Endo 9 - Obesity

Question 1

NE/Epi effect on HSL

Answer 1

increase HSL activity

Question 2

function of HSL

Answer 2

lipolysis (pulls fat out of cells)

Question 3

GH/cortisol effect on HSL

Answer 3

increase HSL activity

Question 4

glucagon effect on HSL

Answer 4

increase HSL activity

Question 5

3 things that increase NE/glucag/GH

Answer 5

fasting
exercise
stress

Question 6

insulin upregulates what enzyme

Answer 6

LPL = more fat into cells

Question 7

insulin blocks what enzyme

Answer 7

HSL

Question 8

most common obesity risk gene

Answer 8

FTO

Question 9

major hormone that suppress food intake

Answer 9

leptin

Question 10

leptin blocks

Answer 10

NPY
AgRP

Question 11

NPYr activation =

Answer 11

FOOD

Question 12

AgRP blocks

Answer 12

melanocortin receptor

Question 13

melanocortin receptor normally =

Answer 13

STOP FOOD

Question 14

location of NPY, AgRP, MSH

Answer 14

Arcuate nucleus

Question 15

location of NPYr and McR

Answer 15

Paraventricular nucleus

Question 16

leptin activates

Answer 16

POMC -> MSH

Question 17

MSH activates

Answer 17

McR

Question 18

T/F high value foods have different brain representations

Answer 18

TRUE

Question 19

what makes us stop eating, weight or calories

Answer 19

weight

Question 20

set point theory =

Answer 20

weight is in homeostasis

Question 21

settling point theory =

Answer 21

set point fluctuates based on input and output

Question 22

3 types of obesity from periphery

Answer 22

system wide metabolic error
fat/muscle function error
nutrient partitioning failure

Question 23

at what bmi does t2dm risk go way up

Answer 23

> 35

Question 24

where is bad fat stored

Answer 24

abdomen

Question 25

best rate to lose pounds

Answer 25

1-2 lb/week

Question 26

when should maintenance be started

Answer 26

6 months after continuous loss