Endo 1 - Introduction Flashcards
2 things glom can do in disease
bleed - red cells in urine (inflammatory process/nephritic syndrome)
leak - proteins get through filtration (nephrotic syndrome)
best way to deliver peptide hormones
injection
target of peptide hormones
gpcr/kinases
3 outcomes of peptide hormones
membrane effects, cellular traffic, enzyme action
delivery of steroid hormones
GI or skin
target of steroid hormones
intracellular receptors that travel to nucleus to affect transcription
usually hormone excess =
down regulation of receptors
usually hormone deficiency =
up regulation of receptors
T/F hormone excess is okay sometimes
T
T/F hormone deficiency = 0 hormone
F (every cell produces a little hormone)
best way to assess gland response
stimulation or suppression of gland
common etiology of endocrine disorders
autoimmune (genetic)
endocrine more common in men or women?
women