Endo

Question 1

Precocious puberty, cafe au lait lesions, asymmetric fibrous dysplasia of bones

Answer 1

McCune Albright syndrome

Question 2

Initial work up when evaluating premature adrenarche in a young boy

Answer 2

testosterone, DHEAS, androstendione, bone age and 17-OHP - these rule out late onset CAH

Question 3

LGA infant with accelerated growth velocity for first 5 years of life, associated with enlarged hands and feet with thickened subQ tissue. Generalized hypotonia

Answer 3

Sotos Syndrome

Question 4

FDA indications for GH supplementation

Answer 4

Prader Wili, turners, SGA without catchup growth by 3 years of age, CKD prior to transplant, SHOX haploinsufficency, noonan syndrome, severe idiopathic short stature

Question 5

Short stature, hypocalcemia, hyperPO4, high PTH, but with PTH resistance

Answer 5

pseudohypoparathyrodisim

Question 6

Labs to draw prior to treatment of acute hypoglycemia

Answer 6

glucose, insulin, cortisol, growth hormone, ketones, lactate and pyruvate

Question 7

Type 1 diabetes, autoimmune thyroid disease, Addison’s disease

Answer 7

Autoimmune polyglandular syndrome type 2

Question 8

Chronic mucocutaneous candidasis, hypoparathyrodisim, addison’s disease, vitiligo, pernicious anemia, diabetes

Answer 8

Autoimmune polyglandular syndrome type 1

Question 9

Central DI, diabetes mellitus, deafness and optic atrophy

Answer 9

Wolfram syndrome

Question 10

Treatment for hypophosphatemic rickets

Answer 10

Phosphorus and calcitriol. Calcitriol helps increase intestinal absorption of phosphorous

Question 11

Evaluation of premature thelarche

Answer 11

bone age, estradiol, LH/FSH

Question 12

What might an infant with congential growth hormone deficiency present with

Answer 12

hypoglycemia, mircopenis an direct hyperbilirubinemia