Encephalitis/Meningitis Flashcards

1
Q

Clinical presentation of encephalitis

A
  • Altered mental status
  • Seizures
  • CN palsies
  • Exaggerated DTR
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2
Q

Physical exam findings for encephalitis

A
  1. Papilledema***
  2. Rash
  3. Autonomic/Hypothalamic disturbances
    • loss of temperature, vasomotor control, SIADH
  4. Arthritis
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3
Q

What would temporal lobe envolvement on MRI in encephalitis case indicate?

A

Herpes simplex virus

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4
Q

Cushings Triad

A
  1. Bradycardia
  2. Respiratory depression
  3. Hypertension
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5
Q

Should CSF be refrigerated?

A

No. kills fastidious organisms like N. meningitidis

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6
Q

Lumbar puncture with CSF that is clear, cloudy, or straw-colored with high protein content and high lymphocytes?

A

viral

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7
Q

When you are concerned for encephalitis who do you call?

A

Infectious disease and Neurology!!!! STAT

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8
Q

What are 5 situations it is important to get CT before LP in encephalitis

A
  1. GCS of <12
  2. New seizures
  3. Focal neuro signs
  4. Papilledema
  5. Immunocompromised
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9
Q

What are 3 things you need to do with an encephalitis patient?

A
  1. Stabilize (intubate, monitor…)
  2. Acyclovir
  3. Isolation
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10
Q

How do you treat someone with increased intracranial pressure

A
  • Elevate head 30-45 degrees
  • Hyperventilate
  • Consider mannitol or corticosteroids
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11
Q

What is the #1 cause of viral meningitis?

A

Enterovirus (coxsackie, herpes (HSV-1))

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12
Q

What organism is most likely to cause bacterial meningitis in: Neonates (<1 month)

A

Group B streptococcus

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13
Q

What organism is most likely to cause bacterial meningitis in babies/children?

A

Streptococcus pneumoniae

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14
Q

What organism is most likely to cause bacterial meningitis in Adults 65+ and immunocompromised patients?

A

Listeria monocytogenes

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15
Q

When are pregnant women screened for group B strept?

A

35-37 weeks

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16
Q

What is the empiric antibiotic treatment for bacterial meningitis?

A

Ceftriaxone + Vancomycin

17
Q

What is the empiric antibiotic treatment for bacterial meningitis in a patient over 50 (greater risk for listeria)

A

Ceftriaxone + Vancomycin + Ampicillin

18
Q

What is the importance of corticosteroids when treating bacterial meningitis?

A

glucocorticoids (dexamethasone), reduce risk of hearing loss from antibiotics

19
Q

Who should receive the quadrivalent meningitis vaccine (serotypes A, C, W, Y)?

A

~2months - 55 years

20
Q

Who should receive meningococcal vaccine?

A

11-18 year olds, vaccinate at age 11-12.

Booster at age 16.

(if initial dose was given at age 16 no need for booster)