Encephalitis Flashcards
1
Q
What are the important facts on JEV?
A
Flavoviridae ssRNA virus
Mosquito born togavirus
> 50% CFR
Epidemic meningoencephalitis
Culex tritaeniorhynchus
Breeds in paddy fields —> rural disease
Morbidity - blindness, ataxia
Pathogenesis - neurotopic and neurotoxic
Supportive Mx and IV 20% Mannitol
Vaccination - Live JE subcut DONT FREEZE
2
Q
What are the important facts on HSV encephalitis?
A
Neonatal form from mother with active HSV 2
Mostly from HSV 1
Due to reactivation from trigeminal ganglion
Neurotoxic to temporal lobe
70% CFR
IV aciclovir for 3 weeks
3
Q
What are the important facts of rabies encephalitis?
A
Rhabdovirus
Bullet shaped ssRNA
Mammalian transmission
Fatal 100%
Unless vaccinated
Passive RIg
Active killed
