Emergency Medicine Flashcards
[EM/Toxicology]
Categories of drug for ‘excited’ (agitation, hypertension, tachycardia, hyperventilation, hyperthermia, mydriasis) (3)
- Anticholinergics (antihistamin, TCA, atropine)
- Sympathomimetics (pseudoephedrine, cocaine, amphetamine)
- Hallucinogens (LSD, Psilocybin)
[EM/Toxicology]
Categories of drugs for ‘depressed’ (obtundation, hypotension, bradycardia, hypoventilation, hypothermia, miosis) (4)
- Cholinergics (organophosphate, insecticides)
- Sympatholytics (clondine)
- Opiates (oxycodone)
- Sedative-hyponitcs (BZ, barbiturates)
[EM/Toxicology]
Anticholinergic toxidrome (7)
Dry, flushed skin
Hyperthermia
Mydriasis
Agitation, delirium, hallucinations
Urinary retention, decreased bowel sounds
Tachycardia, hypertension
[EM/Toxicology]
Cholinergic toxidrome (7)
D
U
M
B
E
L
S
Diarrhea
Urination
Miosis
Bronchorrhea, bronchospasm, bradycardia
Emesis
Lacrimation
Salivation
[EM/Toxicology]
Which toxidrome?
Muscle weakness, fasciculation, paralysis
Respiratory depression, lethargy, seizures, coma
Bradycardia
After Insecticides (organophosphate/carbamate) ingestion
Nicotinic toxidrome
[EM/Toxicology]
Which toxidrome?
CNS depression
Miosis
Respiratory depression/apnea
Bradycardia, hypotension
Opioid toxidrome
[EM/Toxicology]
Which toxidrome (class)?
Agitation, tremors, hallucinations, seizures
Tachycardia, hypertension
Mydriasis
Ingestion of
Pseudoephedrine
Psychostimulants, cocaine, amphetamines
Sympathomimetic toxidrome
[EM/Toxicology]
Which agent?
Sympathomimetic toxidrome (agitation, tachycardia, mydriasis)
With vertical nystagmus, miosis
PCP (Phencyclidine)
[EM/Toxicology]
Examples of anticholinergics (5)
- Antihistamin
- Neuroleptics (chorpromazine, quetiapine)
- Tricyclinc antidepressants
- Atropine
- Antispasmodics (hyoscyamine)
[EM/Toxicology]
Examples of sympathomimetics (5)
- Ephedrine
- Dextromethorphan
- Cocaine
- Amphetamine/methamphetamine
- MDMA (ecstasy)
[EM/Toxicology]
Examples of hallucinogens (3)
- LSD
- PCP
- Mescaline, psilocybin
[EM/Toxicology]
Examples of cholinergics
Insecticides (organophosphate, carbamate)
[EM/Toxicology]
Examples of sympatholytics (1)
Clonidine
[EM/Toxicology/Sadatives]
Examples of sedative-hypnotics (2)
Benzodiazepines
Barbiturates
[EM/Toxicology/AAP]
Acetaminophen minimal toxic dose is
___ mg/kg in < 12 years old
___ g in adults
150 mg/kg in < 12 years old
7.5 g in adolescent/adults
[EM/Toxicology/AAP]
Symptoms of acetaminophen toxicity
Stage 1 (0-24 hours): ___
Stage 2 (1-3 days): ___
Stage 3 (3-4 days): ___
Stage 4 (4-14 days): ___
Stage 1 (0-24 hours): nausea/vomiting, normal LFT
Stage 2 (1-3 days): RUQ pain, Increased LFT, PT/INR
Stage 3 (3-4 days): fulminant hepatic failure, coagulopathy
Stage 4 (4-14 days): recovery or death
[EM/Toxicology/AAP]
Treatment of acetaminophen toxicity
If less than 1 hour: ___
If toxicity is possible: ___
If less than 1 hour: activated charcoal
If toxicity is possible: NAC (N-acetylcysteine)
[EM/Toxicology]
Which ingestion?
Treatment?
Tinitus
GI: Nasuea/vomiting
Respiratory: tachypnea, respiratory alkalosis
Metabolic: anion gap acidosis,
CNS: agitation, coma
Salicylate ingestion
- Treatment:
Alkalinization with sodium bicarbonate
[EM/Toxicology]
Which class drug ingestion and treatment?
Bradycardia, hypotension, ventricular dysrhythmias
Hypoglycemia
Antihypertensives (b-blocker)
(If HYPERglycemia, CCB)
Treatment:
Glucagon
Vasopressor
[EM/Toxicology]
Which class drug ingestion and treatment?
Bradycardia, hypotension, ventricular dysrhythmias
Hyperglycemia
Calcium channel blocker
(HYPOglycemia: b-blocker)
Treatment:
Calcium gluconate
[EM/Toxicology]
Which class drug ingestion?
CNS and respiratory depression, pinpoint pupils, bradycardia
Hypothermia
Anticholinergic effects; dry mouth, constipation
Clonidine (Symphatolytics)
(Opiate: no hypothermia/anticholinergic effects)
[EM/Toxicology/Iron]
5 phases of iron ingestion?
- GI phase (30 min to 6 hours): nausea/vomiting, diarrhea
- Relative stability phase (6 hours to 1 day): asymptomatic
- Systemic toxicity phase (1-3 days): hypovolemic shock, anion gap metabolic acidosis
- Hepatic toxicity (within 2 days)
- GI/pyloric scarring (2-6 weeks): bowel obstruction
[EM/Toxicology/Iron]
Treatment for iron toxicity?
Deferoxamine (if iron level > 500 µg/dL)
[EM/Toxicology]
Which drug ingestion?
Treatment?
Convulsions, coma,
Cardiac dysrhythmias: QRS prolongation
Acidosis
TCA (triCyClic Antidepressants)
- Treatment:
Sodium bicarbonate
[EM/Toxicology]
Serotonin syndrome vs NMS and its treatment
Myoclonus, hyperrefelxia
Hypertension, tachycardia
Confusion, hallucination
Serotonin syndrome (SSRIs, MAOIs)
(Myoclonus is specific to serotonin syndrome)
Treatment:
Benzodiazepine, cyproheptadine
[EM/Toxicology]
Which class of drug ingestion?
Bruxism
Hyponatremia
Hypertension, tachycardia
Confusion, hallucination
MDMA (Ecstasy)
(Bruxism, hyponatremia is specific to Ecstasy)
[EM/Toxicology]
Serotonin syndrome vs NMS
Muscle rigidity: torticolis, protruding tongue
Autonomic instability
Muscle rigidity
Hyperthermia
Confusion
Neuroleptic malignant syndrome
: idiosyncratic drug reaction to antipsychotics or metoclopramide
(Muscle rigidity and autonomic instability is NMS, not in serotonin syndrome)
[EM/Toxicology]
Methemoglobinemia vs CO poisoning, and its treatment?
Low pulse oxymetry
Normal PaO2
Chocolate brown blood
Signs of amyl nitrites ingestion (poppers)
Methemoglobinemia
Treatment: methylene blue
[EM/Toxicology]
Methemoglobinemia vs CO poisoning, and its treatment?
Flulike symptoms
Cherry-red skin
Normal pulse oxymetry
Normal PaO2
CO poisoning
Treatment: high flow oxygen with non-rebreather mask
[EM/Toxicology]
Which metal poisoning and its name?
Lead poisoning
Burton line: blue line along the gum
Basophilic stippling
[EM/Toxicology]
Which chemical poisoning?
Smoke inhalation
Profound lactic acidosis
High oxygen in venous gas
Cyanide poisoning
[EM/Toxicology]
Which chemical poisoning?
Aspiration pneumonitis with ingested
Ventricular arrhythmias when inhaled
(no metabolic acidosis)
Hydrocarbons: gasoline, lighter fluid, etc
[EM/Toxicology]
Ethanol vs methanol vs ethylene glycol and its treatment
CNS depression
Hypothermia
Hypoglycemia
High osmolal gap
High anion gap metabolic acidosis
Ethanol
Treatment:
IV fluid, ABCs, supportive care
[EM/Toxicology]
Ethanol vs methanol vs ethylene glycol and its treatment
Visual disturbance
Abdominal pain
CNS depression
High osmolal gap
High anion gap metabolic acidosis without high lactate or ketones
Methanol: windshield washer, fuel additive
Treatment:
fomepizole
Folinic acid
[EM/Toxicology]
Ethanol vs methanol vs ethylene glycol and its treatment
CNS depression
Acute kidney injury leading to renal failure
High osmolal gap
High anion gap metabolic acidosis without high lactate or ketones
Ethylene glycol: anti-freeze
Treatment:
Socium bicarbonate
Fomepizole
Thiamin, pyridoxine
[EM/Toxicology]
Which chemical poisoning and its treatment?
Cholinergic effects: DUMBLES
Nicotinic: twitching, weakness, paralysis
Organophosphate: pesticides
Treatment:
Atropine
Pralidoxime
[EM/Envenomation]
Which insect bite and its treatment for systemic?
Painless for 2-8 hours
Hemorrhagic blister in 1-2 days
Necrotic ulceration
Some develop systemic symptoms: fever, N/V, myalgias, rash
Brown recluse spider
Treatment:
If systemic, steroid
[EM/Envenomation]
Which insect bite and its treatment?
Pain starts within 30-60 minutes
Rash with hallow target sign
Diaphoresis, muscle cramping, abdominal pain
Agitation
Hypertension
Rhabdomyolysis
Black widow spider
Treatment:
Supportive care
Antivenom is not used due to mortality
[EM/Trauma/Burn]
Burn surface area determination, > 14 years old
Head and neck: ___
Each upper limb: ___
Thorax and abdomen, front: ___
Thorax and abdomen, back: ___
Perineum: ___
Each lower limb: ___
Head and neck: 9%
Each upper limb: 9%
Thorax and abdomen, front: 18%
Thorax and abdomen, back: 18%
Perineum: 1%
Each lower limb: 18%
[EM/Trauma/Burn]
Burn fluid calculation
Parkland formula for 14 years old: ___
ABA criteria for < 14 years old: ___
Parkland formula for 14 years old: 4 ml/kg x BSA
ABA criteria for < 14 years old: 3 ml/kg x BSA
50% in the first 8 hours and the rest in 16 hours
[EM/Trauma/Bone]
Growth plate injuries: Salter-Harris classification
Type 1: S___
Type 2: A___
Type 3: L___
Type 4: T___
Type 5: R___
Type 1: Straight across
Type 2: Above
Type 3: Lower
Type 4: Through
Type 5: Rammed together
[EM/Trauma/Bone]
Name of fracture and its management?
Greenstick fracture: one side of cortex is broken
Management:
If no deformation, immobilization
[EM/Trauma/Bone]
Name of fracture?
Its mechanism and management?
Torus (Buckle) fracture
Mechanism: falling on outstretched hand
Management: immobilization
[EM/Trauma/Bone]
Name of fracture?
Its mechanism and management?
Spiral fracture
Mechanism:
Nonambulatory child - child maltreatment
Toddler - twist or jump
Management: immobilization
[EM/Trauma/Bone]
Name of fracture?
Its mechanism?
Complication if untreated ischemic damage?
Supracondylar fracture
Mechanism: falling on outstretched hand
High risk for neurovascular complications: brachial artery, median/radial nerve
If untreated: Volkmann contractures
[EM/Trauma/Bone]
Diagnosis and its mechanism and treatment?
Acromioclavicular sprain
Mechanism: direct blow to the shoulder
Treatment: Sling immobilizer
[EM/Trauma/Bone]
Diagnosis and its mechanism and treatment?
Anterior shoulder dislocation
Mechanism: abducted, extended, externally rotated shoulder
Treatment: reduction
[EM/Shock]
Target systolic BP minimum in shock?
60 mmHg for 1 month old
70 + 2 x age for > 1 month to 10 years old
90 mmHg for > 10 years old
[EM/Toxicology]
Which drug reaction and its reaction name, treatment?
Intermittent spasmodic contraction
Or sustained involuntary contractions of muscles
: Torticollis, oculogyric crisis, facial grimacing
Chlorpromazine, Promethazine
Dystonic reaction to antipsychotic drugs
Treatment:
Diphenhydramine IV
[EM/Toxicology]
Which chemical toxicity?
Lead poisoning
Linear line in the density of the metaphyses
[EM/Envenomation]
Cause?
From Arizona, New Mexico
Local numbness and swelling without significant erythema
Severe systemic symptoms
- both sympathetic: tachycardia, hyperthermia
- parasympathetic: drooling, wheezing
- neuromuscular symptoms: restlessness, muscular fasciculations, ataxia, abnormal eye movements
Scorpion sting