Embryology of the Heart Flashcards
Angioblastic Cords
Where the body cavities form and arrange themselves side by side
Form the 2 endocardial tubes
Endocardial Tubes
Filled with cardiac jelly
Lateral fold brings the 2 tubes together to form 1 tube
Start the blood flow
1 Tube from Endocardial Tube forms what?
4 chambers of the heart
Cardiac Jelly
develop into the valves of the heart
Early blood flow of the heart
- Sinus Venosus
- Primitive Atria
- Primitive Ventricle
- Bulbus Cordis
- Truncus Arteriosus
- Aortic Sac
Where does blood come from embryologically?
The mother via umbilical cord, caudal end
Bulboventricular Loop
twist/bend of the heart
Atrium and sinus venosus move dorsal
Inflow moved to back of the heart
Outflow moved to front of the heart
Sinus Venosus
Main drain vein of embryo heart
Receives venous blood ergo it makes the SVC and IVC in adult heart
Plays major roll in developing right atrium
Where do the semi-lunar valves form?
Between the bulbus cordis and truncus arteriosus
What forms the atrioventricular valves?
Cardiac jelly
How does the primordial atrium form?
Comes from part of endocardial tube
- Septum premum formation
- Leaves a hole = foramen premum
- Spetum secundum comes down on right side
- Septum premum and septum secundum attach to close off foramen premum
- Septum secundum realizes still need a hole for blood flow
- Formation of foramen secundum = foramen ovale
Foramen Ovale
Closes off at birth due to left pressure being greater than right so a flap comes down and covers the hole.
Becomes fossa ovalis
What forms the right atrium?
sinus venosus
What forms the Right and Left horns of the atrium?
Sinus venosus
What does the Left horn become?
coronary sinus in the right atrium
What does the right horn become?
sinus venarum = smooth muscle of the right atrium
What from the pectinate muscles in right atrium?
primitive atria
What does the coronary sinus separate in the adult heart?
atria from the ventricles
What forms the left atrium?
4 pulmonary vessels
The left atrium is so smooth because it came from veins
What does the left primitive atria become?
left auricle
How does the primordial ventricle change to adult ventricles?
Have the superior and inferior portion of the interventricular septum grow together and form right and left ventricles
This is where VSD’s occur when the growing is deficient
What does the interventricular septum require for proper growth?
endocardial cushions = spot welders that come in from the side
What does the truncus arteriosus become?
ascending aorta and pulmonary trunk
What does the bulbus cordis become?
conus arteriosus of the right ventricle and the aortic vestibule in the left ventricle
How does the outflow of blood form?
Partition the truncus arteriosus and the bulbus cordis
the 2 partitions form ridges that come together and spiral
the spiral motion causes the outflow to split
What is different about fetal circulation?
Bypass the lungs because use the mothers blood which is already oxygenated
What structure allows blood to bypass the lungs?
ductus arteriosus
Which side of the heart has higher pressure before birth?
Right side and after birth the left side as higher pressure