Embryology Basic Body Plan Flashcards

0
Q

four major steps in week one of development

A

fertilization
cleavage
blastocyst formation
implantation

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1
Q

fertilization occurs in

A

the ampulla of the uterine tube

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2
Q

resultant cells of cleavage are called

A

blastomeres

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3
Q

blastomeres are totipotent up to

A

the 4-8 cell stage

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4
Q

16-32 cell stage of cleavage is called

A

morula

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5
Q

2 processes that turn a morula into a blastocyst

A

compaction and cavitation

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6
Q

cleavage occurs between (time)

A

1-4 days

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7
Q

inner cell mass of blastocyst: name, and becomes

A

embryoblast, becomes embryo

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8
Q

outer cell mass of blastocyst, name and becomes

A

trophoblast, becomes fetal portion of placenta

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9
Q

cell type in embryoblast

A

pluripotent stem cells

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10
Q

morula compacts and cavitates to become _____ at _____ (time)

A

blastocyst, 4.5-5 days

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11
Q

blastocyst implants in uterine wall by (time)

A

6-7 days

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12
Q

ruptured follicle becomes

A

corpus luteum

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13
Q

corpus luteum produces

A

progesterone

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14
Q

progesterone does what to the uterus

A

enter secretory phase

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15
Q

which cells of the blastocyst invade the uterine epithelium

A

trophoblasts

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16
Q

what hormone is produced by trophoblasts as they invade uterine epithelium?

A

human Chorionic Gonadotropin (hCG)

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17
Q

Trophoblast during week two

A

differentiates into syncytiotrophoblast (outer layer) and cytotrophoblast (inner layer)

18
Q

embryoblast during week two

A

differentiates into epiblast and hypoblast

19
Q

epiblast during week two

A

secretes fluid to form the amniotic cavity

20
Q

hypoblast in week 2

A

line blastocyst cavity, form primitive yolk sac

21
Q

trophoblast lacunae do what

A

connect to sinusoids in endometrial stroma

22
Q

embryo is embedded in endometrial stroma by (time)

23
Q

new cavity formed by hypoblast in week two

A

chorionic cavity

24
lining of chorionic cavity
extraembryonic mesoserm
25
dizygotic twins constitute ____% of twinning cases
70
26
monozygotic twins constitute ____% of twinning cases
30
27
monozygotic twin spits at early blastocyst
separate amnion, common chorion and placenta
28
monozygotic twins split at late blastocyst
common chorion, amnion and placenta
29
pregnancy without an embryo
hyatidiform mole
30
lab and clinical signs of hyatidiform mole
high hCG, vaginal bleeding, large uterus
31
"It is not birth, marriage, or death, but ________, which is truly the most important time in your life." Lewis Wolpert
gastrulation
32
gastrulation occurs in (time)
week 3
33
gastrulation establishes _______ and defines ________
3 germ layers of the embryo | body axes
34
during gastrulation, epiblast cells
invaginate at the caudal midline (primitive streak) and migrate to replace hypoblast
35
replacement of hypoblast cells with epiblast cells froms
endoderm
36
epiblast cells that migrate between hypoblast and epiblast form
the mesoderm
37
after gastrulation, the epiblast is called
the ectoderm
38
ectoderm becomes
nervous system, epidermis, sensory epithelium of nose, ear, and eye
39
mesoderm becomes
muscle, cartilage, bone, connective tissue, parts of kidney and gonads
40
endoderm becomes
epithelium of gut, epithelium of respiratory system
41
caudal dysgenisis aka
sirenomelia
42
caudal dysgenesis caused by
abnormal gastrulation, migration is disturbed, insufficient caudal mesoderm
43
period of maximal sensitivity to abnormal development
3-8 weeks