Embryology Flashcards
What week does gastrulation occur?
Week 3
What is gastrulation?
Formation of trilaminar layer from the bilaminar layer
What are the 3 germ layers and what do they differentiate in to?
Endoderm - lining of digestive tracts and respiratory tracts
Mesoderm - lining of body cavity and surround organs, muscles, connective tissue, bone, blood vessels
Ectoderm - nervous system, epidermis, enamel of teeth, glands, eye, ear, nose
What week does organogenesis occur?
Week 3-8
What does the mesoderm differentiate into?
Paraxial mesoderm - forms msk trunk
Intermediate mesoderm - forms urogenital system
Lateral mesoderm - forms msk limbs
How is the axial skeleton formed?
Paraxial mesoderm exists as bilateral longitudinal columns either side of the neural tube.
By the end of third week, the columns divide into paired segments at each vertebrae level - somites, starting at the cranial region down to cauda
mesenchymal cells within somites - myotomes, dermatomes, sclerotomes
How is the neural tube formed?
Notochord initiates neurulation, forming neural tube between ectoderm and mesoderm