Embryology Flashcards
Drainage angle
7/40 - neural crest cells from peripheral cornea –> chamber angle
4 mo - Shlemm’s canal
8 mo - drainage angle complete
When does the optic fissure close?
Week 7 ( Day 33)
Lens Placode
Day 27-29
Lens vesicle
Day 30
Primary lens fibres
Day 35
Embryonic nucleus
Day 40
Secondary lens fibres
7 weeks
Ciliary body
3rd month in utero
Ciliary muscle
7 month in utero
Cornea
2 waves of neural crest cells
1st wave - formed between epithelium and lens, forms a double layer of cornea endothelium
2nd wave - between epithelium and endothelium-this zone richly contains hyaluronic acid and collagen fibrils
Descemets membrane
4 months IU
Bowmans membrane
5 months IU
Y lens suture
week 8
Optic Groove
Day 22
Optic vesicles –> pit
Day 23
primordia of superior, inferior, medial rectus and inferior oblique
Day 26
Primordial of lateral rectus appears
Day 27
Cells destined to become RPE acquire pigmentation
Day 28
primordia of superior oblique
Day 29
Closure of embyronic fissure
week 6
Appearance of ciliary ganglion
Week 6
Formation of sclera
Week 7
Appearance of anteiror chamber
3 months
eyelid folds lengthen and fuse
Month 3
differentiation of rods and cones precursors
Month 3
cones fully developed: 6 months
Eyelid separation
Month 5
photoreceptor differentiation
Month 5
Nasolacrimal duct becomes patent
Month 6
Rods differentiate, ora serrata formation
Month 7
completion of anterior chamber angle formation, hyaloid vessel disappear
Month 8
retinal vessels reach temporal periphery, pupillary membrane disappears
Month 9
Which vessels are derived from the ventral ophthalmic artery?
Nasal long Posterior ciliary artery
Which vessels are derived from the dorsal ophthalmic a?
Temporal long posterior ciliary a
CRA
Short posterior ciliary a
When does the eyeball reach its maximum size?
8 years
When does myelination of the optic nerve start and finish?
7 month - 1 mo pp